Researcher
Vanessa Morais
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 2013 → 15 Jun 2015 - Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven) (Lab)
Member
From1 Mar 2009 → 15 Jun 2017
Projects
1 - 3 of 3
- Mitochondrial homeostasis and its importance for neurodegenerative disorders.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Translating genetics of neurodegenerative disorders into therapeutic strategies.From1 Oct 2014 → 30 Sep 2021Funding: BOF - Methusalem
- Mutations in the X-linked intellectual disability gene Ube2a cause neuronal dysfunction and impair Parkin-dependent mitophagyFrom17 Sep 2008 → 4 Jul 2013Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 19
- In Vitro Comparison of the Activity Requirements and Substrate Specificity of Human and Triboleum castaneum PINK1 Orthologues(2016)
Authors: Liesbeth Aerts, Bart De Strooper, Vanessa Morais
- PINK1 activation-turning on a promiscuous kinase(2015)
Authors: Liesbeth Aerts, Bart De Strooper, Vanessa Morais
Pages: 280 - 6 - De regulatie van PINK 1 kinase-activiteit: implicaties voor de ziekte van Parkinson(2015)
Authors: Liesbeth Aerts, Bart De Strooper, Vanessa Morais
- PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402(2015)
Authors: Liesbeth Aerts, Bart De Strooper, Vanessa Morais
Pages: 2798 - 811 - PINK1 Loss of Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling(2014)
Authors: Vanessa Morais, Sven Vilain, Liesbeth Aerts, Lut Overbergh, Patrik Verstreken, Bart De Strooper
Pages: 203 - 207 - The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes(2014)
Authors: Vanessa Morais, Bart De Strooper
Pages: 1363 - 1374 - Near-Infrared 808 nm Light Boosts Complex IV-Dependent Respiration and Rescues a Parkinson-Related pink1 Model(2013)
Authors: Melissa Vos, Vanessa Morais, Bart De Strooper, Patrik Verstreken
- Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 beta: identification of miR-153 target genes with functions related to IA-2 beta in pancreas and brain(2013)
Authors: Wim Mandemakers, Hantao Xu, Vanessa Morais, Samer Matta, Bart De Strooper
Pages: 1547 - 1556 - Mutations in the Intellectual Disability Gene Ube2a Cause Neuronal Dysfunction and Impair Parkin-Dependent Mitophagy(2013)
Authors: Dominik Haddad, Sven Vilain, Melissa Vos, Samer Matta, Bart De Strooper, Hilde Van Esch, Vanessa Morais, Patrik Verstreken
Pages: 831 - 43 - LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis(2012)
Authors: Samer Matta, Wim Mandemakers, Vanessa Morais, Sven Vilain, Dominik Haddad, Lucia Chavez Gutierrez, Eric Karran, Matthew Holt, Bart De Strooper, Patrik Verstreken
Pages: 1008 - 1021
Patents
1 - 6 of 6
- Means and methods for treatment of early-onset parkinson's disease (Inventor)
- Means and methods for treatment of early-onset parkinson's disease (Inventor)
- Restoring phosphorylation of a novel pink1 substrate to treat parkinson's disease (Inventor)
- Restoring phosphorylation of a novel pink1 substrate to treat parkinson's disease (Inventor)
- Means and methods for treatment of early-onset parkinson's disease (Inventor)
- RESTORING PHOSPHORYLATION OF A NOVEL PINK1 SUBSTRATE TO TREAT PARKINSON'S DISEASE (Inventor)