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Researcher
Wim Dehaen
- Disciplines:Condensed matter physics and nanophysics, Analytical chemistry, Inorganic chemistry, Organic chemistry, Physical chemistry, Pharmaceutical analysis and quality assurance
Affiliations
- Sustainable Chemistry for Metals and Molecules (Division)
Member
From1 Oct 2004 → Today
Projects
11 - 20 of 71
- Synthesis of fused isothiazole derivatives as inhibitors of cyclin G associated kinase (GAK) and phosphoinositide kinase FYVE-type zinc finger (PIKfyve)From26 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Oxapillar[m]arene[n]quinones (OPAQs): a novel class of promising macrocyclic hostsFrom30 Aug 2022 → TodayFunding: FWO fellowships, BOF - doctoral mandates
- Development of new ligands for selective separation of americiumFrom21 Aug 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Valorization of Aloe vera processing wasteFrom11 Aug 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Optimisation of a triterpene lead compound for the development of pan-anticoronavirus drugs targeting nsp15From3 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Synthesis and structure-activity relationship studies of CCR8 agonists as a novel treatment option for autoimmune diseasesFrom27 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Development of chelators for 225Ac-based radiopharmaceuticalsFrom1 Oct 2021 → TodayFunding: SCK (Study Centre Nuclear Energy)
- Chemically modified polysaccharides (CMP) coatings for site-specific drug delivery to the colonFrom14 Apr 2021 → 1 Jun 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Ultra-permeable Macrocycle-based Membranes: Design, Fabrication and ApplicationFrom22 Jan 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A novel class of reversible Exportin-1 inhibitors for cancer therapyFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
Publications
1 - 10 of 494
- Pillararene-inspired arenes: Synthesis, properties and applications compared to the parent macrocycle(2024)
Authors: Sem Bleus, Wim Dehaen
- Constructing ultra-permeable pillar[5]arene-based membrane with intramolecular water channels and precise molecular fractionation(2024)
Authors: Sem Bleus, Linde Achten, Samuel Eyley, Wim Thielemans, Ivo Vankelecom, Wim Dehaen, Xing Yang
- Covalent immobilization of N-heterocyclic carbenes on pristine carbon substrates: from nanoscale characterization to bulk catalysis(2024)
Authors: Sven Bernaerts, Samuel Eyley, Wim Thielemans, Wim Dehaen, Steven De Feyter
Pages: 1432 - 1435 - A Highly Efficient Strategy for One-Pot and Pseudo-Six-Component Synthesis of Hexahydroquinolines(2024)
Authors: Wim Dehaen, Linde Achten
Pages: 4466 - 4473 - Synthesis of benzo[d]isothiazoles: an update(2024)
Authors: Yulia Ivanova, Steven De Jonghe, Wim Dehaen
- Cycloaddition reactions of heterocyclic azides with 2-cyanoacetamidines as a new route to C,N-diheteroarylcarbamidines(2024)
Authors: Wim Dehaen
Pages: 17 - 24 - New sugar-incorporated N-heterocyclic carbene precursors and their Ag(I) and Pd(II) complexes: Synthesis, characterization, and cytotoxicity studies(2024)
Authors: Dirk Daelemans, Wim Dehaen, Luc Van Meervelt
- Exploration of 1,2,3-triazolo fused triterpenoids as inhibitors of human coronavirus 229E targeting the viral nsp15 protein(2024)
Authors: Annelies Stevaert, Benjamin Van Loy, Lieve Naesens, Wim Dehaen
- BOPAM: Efficient Synthesis of a Bright Asymmetric Bis-Boron Complex and its Dark Side(2024)
Authors: Flip de Jong, Jonathan Vandenwijngaerden, Luc Van Meervelt, Mark Van der Auweraer, Wim Dehaen
- The first BOAHY-based probe for ClO- : Synthesis, spectral investigations and selective recognition behaviour(2024)
Authors: Luc Van Meervelt, Wim Dehaen
Patents
1 - 10 of 10
- Isoquinoline and pyridine based cxcr4 antagonists (Inventor)
- Phosphonucleosides useful in the treatment of viral disorders (Inventor)
- Novel anti-cancer thiophene compounds (Inventor)
- Phosphonate nucleosides useful in the treatment of viral diseases (Inventor)
- Phosphonucleosides useful in the treatment of viral disorders (Inventor)
- Phosphonate nucleosides useful in the treatment of viral diseases (Inventor)
- Anti-cancer compounds (Inventor)
- Phosphonate nucleosides useful in the treatment of viral diseases (Inventor)
- EXO OLEFIN-CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF (Inventor)
- PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS (Inventor)