Researcher
Wim Van Hul
- Research Expertise:Genetic analyses of obesity and comorbidities and skeletal dysplasias
- Keywords:SKELETAL DYSPLASIAS, OBESITY, PAGET DISEASE, GENETIC DISEASE, Biomedical sciences (incl. biochemistry)
- Disciplines:Endocrinology and metabolic diseases, Molecular and cell biology, Metabolic diseases, Genetics
- Research techniques:DNA-sequencing, Next generation sequencing, cloning, expression studies, cell cultures, animal models (mouse and zebrafish)
- Users of research expertise:teams with complementary expertise and interest
Affiliations
- Medical Genetics (MEDGEN) (Research group)
Member
From1 Oct 2022 → Today - Medical genetics of obesity and skeletal disorders (MGENOS) (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2022
Projects
1 - 10 of 27
- Precision Medicine Technologies (PreMeT)From1 Jan 2021 → TodayFunding: IOF - mandates
- Unraveling the Role of Paraoxonase 1 and 3 in the Etiology and Progression of Obesity and Obesity-Associated Liver Disease.From1 Nov 2020 → TodayFunding: FWO fellowships
- GENOmics in MEDicine: From whole genome sequencing towards personalized medicine (GENOMED).From3 Jul 2019 → TodayFunding: BOF - Methusalem, Fund Recuperation Fiscal Exemption
- The role of the paraoxonase gene family in obesity and obesity-associated liver disease following exposure to environmental pollutants or medical intervention strategies.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Functional evaluation of the role of LRP4 and NPR3 in the regulation of bone metabolism by regulating respectively bone mass and bone growth.From1 Oct 2017 → 30 Sep 2020Funding: FWO fellowships
- Paget's disease of bone: molecular genetic investigation of the NFkB signaling regulating genes CBL, CBLB, and NR4A1 and functional validation in vitro and in Danio rerio.From1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Gene identification and zebrafish disease modeling of inherited bone disordersFrom1 Jan 2017 → 31 Dec 2021Funding: FWO scientific research network
- Study on the role of LRP4 in the regulation of Wnt signaling and bone formation.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- GENOMED - Genomics in Medicine.From1 Jan 2015 → 31 Dec 2019Funding: BOF - Other initiatives, Fund Recuperation Fiscal Exemption
- Evaluation of the role of LRP4 in the regulation of Wnt/Bcatenin dependent Wnt signalling and bone formation.From1 Oct 2013 → 30 Sep 2016Funding: FWO fellowships
Publications
31 - 40 of 177
- Insights into the multifactorial causation of obesity by integrated genetic and epigenetic analysis(2020)
Authors: Sara Diels, Wim Vanden Berghe, Wim Van Hul
- Germline and mosaic variants in PRKACA and PRKACB cause a multiple congenital malformation syndrome(2020)
Authors: Adrian Palencia-Campos, Phillip C. Aoto, Erik M.F. Machal, Ana Rivera-Barahona, Patricia Soto-Bielicka, Daniela Bertinetti, Blaine Baker, Lily Vu, Francesca Piceci-Sparascio, Isabella Torrente, et al.
Pages: 977 - 988 - Copy number variant analysis and expression profiling of the olfactory receptor-rich 11q11 region in obesity predisposition(2020)
Authors: Sara Diels, Sander Huybreghts, Guy Massa, An Verrijken, Stijn Verhulst, Wim Van Hul
- Unmet therapeutic, educational and scientific needs in parathyroid disorders(2019)
Authors: Jens Bollerslev, Camilla Schalin-Jantti, Lars Rejnmark, Heide Siggelkow, Hans Morreau, Rajesh Thakker, Antonio Sitges-Serra, Filomena Cetani, Claudio Marcocci, Andrea Guistina, et al.
Pages: P1 - P19 - Familial Paget's disease of bone(2019)
Authors: Josephine J. M. Peeters, Raphaël De Ridder, Esther C. Hamoen, E. Marelise W. Eekhoff, Frits Smit, Eveline Boudin, Wim Van Hul, Socrates E. Papapoulos, Natasha M. Appelman-Dijkstra
- Clinical, molecular genetics and therapeutic aspects of syndromic obesity(2019)
Authors: Ellen Geets, Marije Meuwissen, Wim Van Hul
Pages: 23 - 40 - Camurati-Engelmann disease(2019)
Authors: Wim Van Hul, Eveline Boudin, Geert Mortier
Pages: 554 - 560 - Genetic variation in RIN3 in the Belgian population supports its involvement in the pathogenesis of Paget's disease of bone and modifies the age of onset(2019)
Authors: Raphaël De Ridder, Eveline Boudin, Geert Vandeweyer, Jean-Pierre Devogelaer, Erik Fransen, Geert Mortier, Wim Van Hul
Pages: 613 - 621 - Assessment of the genetic and clinical determinants of fracture risk(2018)
Authors: Katerina Trajanoska, John A. Morris, Ling Oei, Wim Van Hul, et al.
- Targeted search for genetic causes of the Prader Willi like phenotype(2018)
Authors: Wim Van Hul
Number of pages: 259