Researcher
Wim Van Hul
- Research Expertise:Genetic analyses of obesity and comorbidities and skeletal dysplasias
- Keywords:SKELETAL DYSPLASIAS, OBESITY, PAGET DISEASE, GENETIC DISEASE, Biomedical sciences (incl. biochemistry)
- Disciplines:Endocrinology and metabolic diseases, Molecular and cell biology, Metabolic diseases, Genetics
- Research techniques:DNA-sequencing, Next generation sequencing, cloning, expression studies, cell cultures, animal models (mouse and zebrafish)
- Users of research expertise:teams with complementary expertise and interest
Affiliations
- Medical Genetics (MEDGEN) (Research group)
Member
From1 Oct 2022 → Today - Medical genetics of obesity and skeletal disorders (MGENOS) (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2022
Projects
1 - 10 of 27
- Precision Medicine Technologies (PreMeT)From1 Jan 2021 → TodayFunding: IOF - mandates
- Unraveling the Role of Paraoxonase 1 and 3 in the Etiology and Progression of Obesity and Obesity-Associated Liver Disease.From1 Nov 2020 → TodayFunding: FWO fellowships
- GENOmics in MEDicine: From whole genome sequencing towards personalized medicine (GENOMED).From3 Jul 2019 → TodayFunding: BOF - Methusalem, Fund Recuperation Fiscal Exemption
- The role of the paraoxonase gene family in obesity and obesity-associated liver disease following exposure to environmental pollutants or medical intervention strategies.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Functional evaluation of the role of LRP4 and NPR3 in the regulation of bone metabolism by regulating respectively bone mass and bone growth.From1 Oct 2017 → 30 Sep 2020Funding: FWO fellowships
- Paget's disease of bone: molecular genetic investigation of the NFkB signaling regulating genes CBL, CBLB, and NR4A1 and functional validation in vitro and in Danio rerio.From1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Gene identification and zebrafish disease modeling of inherited bone disordersFrom1 Jan 2017 → 31 Dec 2021Funding: FWO scientific research network
- Study on the role of LRP4 in the regulation of Wnt signaling and bone formation.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- GENOMED - Genomics in Medicine.From1 Jan 2015 → 31 Dec 2019Funding: BOF - Other initiatives, Fund Recuperation Fiscal Exemption
- Evaluation of the role of LRP4 in the regulation of Wnt/Bcatenin dependent Wnt signalling and bone formation.From1 Oct 2013 → 30 Sep 2016Funding: FWO fellowships
Publications
41 - 50 of 177
- Human genetics of sclerosing bone disorders(2018)
Authors: Raphaël De Ridder, Eveline Boudin, Wim Van Hul
Pages: 256 - 268 - Sclerosing bone dysplasias(2018)
Authors: Eveline Boudin, Wim Van Hul
Pages: 707 - 723 - Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis(2018)
Authors: Gretl Hendrickx, Vere Borra, Ellen Steenackers, Timur A. Yorgan, Christophe Hermans, Eveline Boudin, Jérôme J. Waterval, Ineke D.C. Jansen, Tolunay Beker Aydemir, Niels Kamerling, et al.
- Bi-allelic loss-of-function mutations in the NPR-C receptor result in enhanced growth and connective tissue abnormalities(2018)
Authors: Eveline Boudin, Tjeerd R. de Jong, Tim C. R. Prickett, Bruno Lapauw, Kaatje Toye, Viviane O M Van Hoof, Aline Verstraeten, Hugo S. A. Heymans, Eelco Dulfer, Lut Van Laer, et al.
Pages: 288 - 295 - Evaluation of a role for NPY and NPY2R in the pathogenesis of obesity by mutation and copy number variation analysis in obese children and adolescents(2018)
Authors: Laure Sorber, Sigri Beckers, An Verrijken, Guy Massa, Stijn Verhulst, Wim Van Hul
Pages: 1 - 10 - Sclerosing bone disorders(2018)
Authors: Eveline Boudin, Wim Van Hul
Pages: 507 - 518 - DNA sequencing and copy number variation analysis of MCHR2 in a cohort of Prader Willi like (PWL) patients(2018)
Authors: An Verrijken, Stijn Verhulst, Wim Van Hul
Pages: 158 - 166 - Fibrogenesis imperfecta ossium and response to human growth hormone(2017)
Authors: Sanjay Kumar Bhadada, Vandana Dhiman, Soham Mukherjee, Sameer Aggarwal, Amanjit Bal, Suja P. Sukumar, Ashwani Sood, Dinesh Chandra Sharma, Niranjan Khandelwal, Anil Bhansali, et al.
Pages: 1750 - 1756 - Genetic screening of WNT4 and WNT5B in two populations with deviating bone mineral densities(2017)
Authors: Gretl Hendrickx, Eveline Boudin, Ellen Steenackers, Torben Leo Nielsen, Marianne Andersen, Kim Brixen, Wim Van Hul
Pages: 244 - 249 - The Lrp4 R1170Q homozygous knock-in mouse recapitulates the bone phenotype of sclerosteosis in humans(2017)
Authors: Eveline Boudin, Timur Yorgan, Igor Fijalkowski, Stephan Sonntag, Ellen Steenackers, Gretl Hendrickx, Annelies De Maré, Thorsten Schinke, Wim Van Hul
Pages: 1739 - 1749