Researcher
Xaveer Van Ostade
- Research Expertise:Purification and characterisation of proteins and protein complexes.
- Keywords:HPLC ANALYSIS, PROTEIN PURIFICATION, LC-MASS SPECTROMETRY, PROTEIN BIOCHEMISTRY, PROTEIN COMPLEX IDENTIFICATION, PROTEIN CHARACTERIZATION, HPLC-MS, MASS SPECTROMETRY (TANDEM), Biomedical sciences (incl. biochemistry)
- Disciplines:Biochemistry and metabolism, Systems biology, Diagnostics, Laboratory medicine, Medical biochemistry and metabolism, Medicinal products
- Research techniques:- Basic protein techniques - Tandem Affinity Purification (TAP) - Microcapillary 2D-HPLC - Mass spectrometry (ESI-QTOF, MALDI-TOF-TOF) - Basic DNA cloning techniques
- Users of research expertise:Academic research teams Pharmaceutical industry
Affiliations
- Cell death signaling (CDS) (Research group)
Member
From1 Jan 2024 → Today - Proteinscience, proteomics and epigenetic signaling (PPES) (Research group)
Member
From1 Oct 2021 → 31 Dec 2023 - Proteinchemistry, proteomics and epigenetic signalling(PPES) (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2021
Projects
11 - 20 of 22
- Regulation and interaction between the morphological switch and the mannosylerythritol lipids (MEL) production in the yeast Pseudozyma aphidis DSM70725.From1 Jan 2014 → 31 Dec 2014Funding: BOF - Other initiatives
- Analysis of the intracellular mechanism of Withaferin A, a plant steroidal compound with antitumor characteristics.From1 Jan 2013 → 31 Dec 2013Funding: BOF - Other initiatives
- Quantitative proteomic characterization of cellular targets of withaferin A involved in cancer therapy chemosensitisation in B-cell chronic leukemia cells.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Identification of biomarkers using proteomics to detect cervical cancer.From1 Jan 2012 → 31 Dec 2013Funding: IWT personal funding - strategic basic research grants
- Ion mobility high resolution mass spectrometer: a strong tool for fragile structures.From22 Jul 2010 → 21 Jul 2015Funding: Hercules - Small and Medium size research infrastructure
- Characterisation of epigenetic control of cancer-inflammation by jumonji histone demethylases during hypoxiaFrom1 Jul 2010 → 31 Dec 2014Funding: BOF - Doctoral projects
- Identification of biomarkers using proteomics to detect cervical cancer.From1 Jan 2010 → 31 Dec 2011Funding: IWT personal funding - strategic basic research grants
- Design of an animal product-free culture expansion platform for human adult progenitor cells (FREESTEM).From1 Oct 2009 → 31 Mar 2011Funding: IWT / VLAIO - indirect funding by business world
- High performance LC-tandem mass spectrometry as necessary equipment for strategic research elucidation of chemical biomolecules and quantitative determination of medicines, metabolites and biomolecules in biological matrices.From19 Dec 2008 → 18 Dec 2013Funding: Own budget, for example: patrimony, inscription fees, gifts, Hercules - Small and Medium size research infrastructure
- Study of HIV resistance in the female genital tract by proteomics.From1 Oct 2008 → 31 May 2010Funding: FWO fellowships
Publications
1 - 10 of 46
- Adverse drug reactions during COVID-19 treatment(2023)
Authors: Lizette Gil-del-Valle, Rosario Gravier-Hernández, Waldemar Baldoquin-Rodríguez, Beatriz Sierra-Vázquez, Ana Beatriz Perez-Díaz, Pablo Sariol-Resik, Tatiana Prieto-Dominguez, Mario Manuel Delgado-Guerra, Joniel Arnoldo Sánchez- Márquez, Olga Elena López-Fernández, et al.
Pages: 1 - 12 - Chronic exposure to multiple stressors alters the salivary proteome of piglets(2023)
Authors: Xaveer Van Ostade, Miriam Ayuso Hernando, Martin Dom, Geert Van Raemdonck, Steven Van Cruchten, Christophe Casteleyn, Chris Van Ginneken
Pages: 1 - 22 - Mas-related G protein-coupled receptors(2023)
Authors: Rohit Arora, Alain Labro, Xaveer Van Ostade
Number of pages: 187 - Virus-host interactions in the chikungunya virus replication cycle(2022)
Authors: Lien De Caluwé, Kevin Ariën, Xaveer Van Ostade, Koen Bartholomeeusen
Number of pages: 188 - The CD147 protein complex is involved in entry of Chikungunya virus and related alphaviruses in human cells(2021)
Authors: Lien De Caluwe, Sandra Coppens, Katleen Vereecken, Simon Daled, Maarten Dhaenens, Xaveer Van Ostade, Dieter Deforce, Kevin Ariën, Koen Bartholomeeusen
- Triage of human papillomavirus infected women by methylation analysis in first-void urine(2021)
Authors: Severien Van Keer, Annina P. van Splunter, Jade Pattyn, Annemie De Smet, Sereina Herzog, Xaveer Van Ostade, Wiebren Tjalma, Margareta Ieven, Pierre Van Damme, Renske D.M. Steenbergen, et al.
- Covalent cysteine targeting of Bruton’s tyrosine kinase (BTK) family by withaferin-A reduces survival of glucocorticoid-resistant multiple myeloma MM1 cells(2021)
Authors: Emilie Logie, Chandra Sekhar Chirumamilla, Claudina Perez Novo, Priyanka Shaw, Ken Declerck, Ajay Palagani, Savithri Rangarajan, Bart Cuypers, Nicolas De Neuter, Fazil Mobashar Hussain Urf Turabe, et al.
- Towards a proteome based description of the Withaferin A antitumor properties(2021)
Authors: Martin Dom, Xaveer Van Ostade, Wim Vanden Berghe
Number of pages: 270 - Broad-spectrum antitumor properties of Withaferin A(2020)
Authors: Martin Dom, Wim Vanden Berghe, Xaveer Van Ostade
Pages: 30 - 50 - Experimental evidence on the nature of the antigen in the direct agglutination test for visceral leishmaniasis(2020)
Authors: Vera Kühne, Ruben Verstraete, Xaveer Van Ostade, Philippe Büscher
Pages: 788 - 796