Researcher
Yvan Vander Heyden
- Research Expertise:
- Analytical chemistry Development
- Optimization and validation of separation methods (HPLC, CE, CEC)
- Data analysis: metrology and chemometrics
- Keywords:Pharmacy and pharmacology, Medicine
- Disciplines:Separation techniques, Spectrometry, Instrumental methods, Biomarker discovery, Analytical chemistry not elsewhere classified, Phytochemistry, Pharmaceutical analysis and quality assurance not elsewhere classified, Analytical separation and detection techniques, Chemometric techniques
- Users of research expertise:
- Analytical chemistry Development
- Optimization and validation of separation methods (HPLC, CE, CEC)
- Data analysis: metrology and chemometrics
Affiliations
- Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling (Research group)
Responsible
From1 Jan 2015 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From8 Apr 2019 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Analytical Chemistry and Pharmaceutical Technology (Department)
Member
From1 May 2003 → 31 Dec 2013 - Pathologic Biochemistry and Physiology (Department)
Member
From1 Oct 2001 → 30 Sep 2003 - Analytical Chemistry and Pharmaceutical Technology (Department)
Member
From1 Oct 1991 → 31 Mar 2004
Projects
1 - 10 of 16
- REVALUATION OF ANDEAN ANCESTRAL KNOWLEDGE ON MEDICINAL HERBS THROUGH THE DEVELOPMENT OF A PHYTOTHERAPEUTIC PRODUCTFrom1 Sep 2023 → TodayFunding: VLIR-UOS Short Training Schorlarships
- Achiral and chiral targeted brain metabolomics in volume-limited samples: quest for broad coverage, sensitivity and throughput using chemical derivatization and miniaturized liquid chromatography tandem mass spectrometry.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Combination of Molecular Dynamics and Quantitative Structure Enantioselective Relationships (QSER) models to elucidate enantiorecognition mechanisms on polysaccharide and antibiotic based chiral selectorsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Modern chiral separation strategies: a tool to facilitate the development of QSRR modelsFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- advanced Metabolomics Platform consisting of two complementary LC-MS/MS analyzersFrom1 May 2016 → 30 Apr 2020Funding: Hercules - Small and Medium size research infrastructure
- Fast metabolite profiles and their data analysis for the prospective study and quality control of plants of pharmaceutical interestFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- ULB-VUB Joint Research Group: Brussels (Bio)Pharmaceutical Analysis Research Group - BBRGFrom5 Nov 2014 → 3 Dec 2022Funding: University - Project driven research
- Chemometrics and metabolite profiles for the prospective study and quality control of plants of pharmaceutical interest: bringing this untapped approach into the fieldFrom1 Sep 2013 → 31 Aug 2016Funding: FWO research project (including WEAVE projects)
- Design space approach for the validation of an innovative continuous pharmaceutical production process.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- Support Vector Machines in Pharmaceutical AnalysisFrom1 Feb 2011 → 31 Jan 2012Funding: FWO visiting post-doctoral fellowship
Publications
11 - 20 of 168
- Development of an adverse outcome pathway network for breast cancer: a comprehensive representation of the pathogenesis, complexity and diversity of the disease(2022)
Authors: Gigly Del'Haye, Ine Nulmans, Sandrine Paula Bouteille, Karolien Sermon, Brecht Wellekens, Matthias Rombaut, Tamara Vanhaecke, Yvan Vander Heyden, Joery De Kock
Pages: 2881-2897 - Authentication of extra virgin Argan oil by selected-ion flow-tube mass-spectrometry fingerprinting and chemometrics(2022)
Authors: Mourad Kharbach, Huiwen Yu, Rabie Kamal, Ilias Marmouzi, Katim Alaoui, Joeri Vercammen, Abdelaziz Bouklouze, Yvan Vander Heyden
- Fabrication of a molecularly imprinted monolithic column via the epitope approach for the selective capillary microextraction of neuropeptides in human plasma(2022)
Authors: Xiaoyun LEI, Ting Huang, Xiaoping Wu, Debby Mangelings, Ann Van Eeckhaut, Jana Bongaerts, Herman Terryn, Yvan Vander Heyden
- Secondary-metabolites fingerprinting of Argania spinosa kernels using liquid chromatography-mass spectrometry and chemometrics, for metabolite identification and quantification as well as for geographic classification(2022)
Authors: Mourad Kharbach, Johan Viaene, Huiwen Yu, Rabie Kamal, Ilias Marmouzi, Abdelaziz Bouklouze, Yvan Vander Heyden
- Development of a capillary electrophoresis method for the separation of flavonolignans in silymarin complex(2022)
Authors: Petra Riasová, Jaroslav Jenčo, David Moreno-González, Yvan Vander Heyden, Debby Mangelings, Miroslav Polášek, Pavel Jáč
Pages: 930-938 - In vitro antimycobacterial activity of medicinal plants Lantana camara, Cryptolepis sanguinolenta, and Zanthoxylum leprieurii(2022)
Authors: Naasson Tuyiringire, Ivan Taremwa Mugisha, Deusdedit Tusubira, Jean-Pierre Munyampundu, Claude Mambo Muvunyi, Yvan Vander Heyden
- Coupling of chiral and achiral stationary phases in supercritical fluid chromatography(2022)
Authors: Petra Riasová, Pavel Jáč, Miroslav Polášek, Yvan Vander Heyden, Debby Mangelings
- Modelling approaches for chiral chromatography on polysaccharide-based and macrocyclic antibiotic chiral selectors: A review(2022)
Authors: Pieter De Gauquier, Kenno Vanommeslaeghe, Yvan Vander Heyden, Debby Mangelings
- Azepine-Indole Alkaloids From Psychotria nemorosa Modulate 5-HT2A Receptors and Prevent in vivo Protein Toxicity in Transgenic Caenorhabditis elegans(2022)
Authors: Benjamin Kirchweger, Luiz Carlos Klein-Junior, Dagmar Pretsch, Ya Chen, Sylvian Cretton, André L. Gasper, Yvan Vander Heyden, Philippe Christen, Johannes Kirchmair, Amélia T. Henriques, et al.
- Improved modelling for low-correlated multiple responses by common-subset-of-independent-variables partial-least-squares(2022)
Authors: Jan P M Andries, Gerjen H Tinnevelt, Yvan Vander Heyden