Researcher
Yvan Vander Heyden
- Research Expertise:
- Analytical chemistry Development
- Optimization and validation of separation methods (HPLC, CE, CEC)
- Data analysis: metrology and chemometrics
- Keywords:Pharmacy and pharmacology, Medicine
- Disciplines:Separation techniques, Spectrometry, Instrumental methods, Biomarker discovery, Analytical chemistry not elsewhere classified, Phytochemistry, Pharmaceutical analysis and quality assurance not elsewhere classified, Analytical separation and detection techniques, Chemometric techniques
- Users of research expertise:
- Analytical chemistry Development
- Optimization and validation of separation methods (HPLC, CE, CEC)
- Data analysis: metrology and chemometrics
Affiliations
- Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling (Research group)
Responsible
From1 Jan 2015 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From8 Apr 2019 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Analytical Chemistry and Pharmaceutical Technology (Department)
Member
From1 May 2003 → 31 Dec 2013 - Pathologic Biochemistry and Physiology (Department)
Member
From1 Oct 2001 → 30 Sep 2003 - Analytical Chemistry and Pharmaceutical Technology (Department)
Member
From1 Oct 1991 → 31 Mar 2004
Projects
1 - 10 of 15
- Achiral and chiral targeted brain metabolomics in volume-limited samples: quest for broad coverage, sensitivity and throughput using chemical derivatization and miniaturized liquid chromatography tandem mass spectrometry.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Combination of Molecular Dynamics and Quantitative Structure Enantioselective Relationships (QSER) models to elucidate enantiorecognition mechanisms on polysaccharide and antibiotic based chiral selectorsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Modern chiral separation strategies: a tool to facilitate the development of QSRR modelsFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- advanced Metabolomics Platform consisting of two complementary LC-MS/MS analyzersFrom1 May 2016 → 30 Apr 2020Funding: Hercules - Small and Medium size research infrastructure
- Fast metabolite profiles and their data analysis for the prospective study and quality control of plants of pharmaceutical interestFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- ULB-VUB Joint Research Group: Brussels (Bio)Pharmaceutical Analysis Research Group - BBRGFrom5 Nov 2014 → 3 Dec 2022Funding: University - Project driven research
- Chemometrics and metabolite profiles for the prospective study and quality control of plants of pharmaceutical interest: bringing this untapped approach into the fieldFrom1 Sep 2013 → 31 Aug 2016Funding: FWO research project (including WEAVE projects)
- Design space approach for the validation of an innovative continuous pharmaceutical production process.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- Support Vector Machines in Pharmaceutical AnalysisFrom1 Feb 2011 → 31 Jan 2012Funding: FWO visiting post-doctoral fellowship
- The role of VHHs or Nanobodies during the final period of poliovirus eradicationFrom1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
Publications
31 - 40 of 168
- Improved multi-class discrimination by Common-Subset-of-Independent-Variables Partial-Least-Squares Discriminant Analysis(2021)
Authors: Jan P.M. Andries, Yvan Vander Heyden
- In Vitro & In Vivo Anti-Hyperglycemic Potential of Saponins Cake and Argan Oil from Argania spinosa(2021)
Authors: Rabie Kamal, Mourad Kharbach, Yvan Vander Heyden, Huiwen Yu, Abdelaziz Bouklouze, Yahia Cherrah, Katim Alaoui
- New insights into the Argan oil categories characterization: chemical descriptors, FTIR fingerprints, and chemometric approaches.(2021)
Authors: Mourad Kharbach, H. Yu, Rabie Kamal, Issam Barra, Ilias Marmouzi, Yahia Cherrah, Katim Alaoui, , Yvan Vander Heyden
- Feasibility study on exhaled-breath analysis by untargeted Selected-Ion Flow-Tube Mass Spectrometry in children with cystic fibrosis, asthma, and healthy controls: comparison of data pretreatment and classification techniques.(2021)
Authors: Karen Segers, Amorn Slosse, Johan Viaene, Michiel A.G.E. Bannier, Kim D.G. Van de Kant, Edward Dompeling, Ann Van Eeckhaut, Joeri Vercammen, Yvan Vander Heyden
- Sequential optimization methods.(2021)Edition: 3Series: Structural and Multidisciplinary OptimizationVolume: 63
Authors: Bieke Dejaegher, Yvan Vander Heyden
Pages: 553-572Number of pages: 17 - Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica)(2021)
Authors: Ziyad Ben Ahmed, Mohamed Yousfi, Johan Viaene, Bieke Dejaegher, Kristiaan Demeyer, Yvan Vander Heyden
- Extra Virgin Argan oils’ shelf-life monitoring and prediction based on chemical properties or FTIR fingerprints and chemometrics.(2021)
Authors: Mourad Kharbach, Ilias Marmouzi, Rabie Kamal, Huiwen Yu, Issam Barra, Yahia Cherrah, Katim Alaoui, Yvan Vander Heyden, Abdelaziz Bouklouze
- Method development in metabolomics and its application as diagnostic tool(2021)
Authors: Karen Segers, Ann Van Eeckhaut, Yvan Vander Heyden, Debby Mangelings, Ilse Smolders, Dimitri De Bundel
Number of pages: 260 - Anti-Cancer Activity of Curcumin on Multiple Myeloma.(2021)
Authors: H. Mirzaei, H. Bagheri, F. Ghasemi, J.M. Khoi, M.H. Pourhanifeh, Yvan Vander Heyden, E. Mortezapour, A. Nikdasti, P. Jeandet, H. Khan, et al.
Pages: 575-586 - Improvement of quantitative structure–retention relationship models for chromatographic retention prediction of peptides applying individual local partial least squares models.(2020)
Authors: Jan P.M. Andries, Mohammad Goodarzi, Yvan Vander Heyden