Researcher
Yvan Vander Heyden
- Research Expertise:
- Analytical chemistry Development
- Optimization and validation of separation methods (HPLC, CE, CEC)
- Data analysis: metrology and chemometrics
- Keywords:Pharmacy and pharmacology, Medicine
- Disciplines:Separation techniques, Spectrometry, Instrumental methods, Biomarker discovery, Analytical chemistry not elsewhere classified, Phytochemistry, Pharmaceutical analysis and quality assurance not elsewhere classified, Analytical separation and detection techniques, Chemometric techniques
- Users of research expertise:
- Analytical chemistry Development
- Optimization and validation of separation methods (HPLC, CE, CEC)
- Data analysis: metrology and chemometrics
Affiliations
- Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling (Research group)
Responsible
From1 Jan 2015 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From8 Apr 2019 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Analytical Chemistry and Pharmaceutical Technology (Department)
Member
From1 May 2003 → 31 Dec 2013 - Pathologic Biochemistry and Physiology (Department)
Member
From1 Oct 2001 → 30 Sep 2003 - Analytical Chemistry and Pharmaceutical Technology (Department)
Member
From1 Oct 1991 → 31 Mar 2004
Projects
1 - 10 of 16
- REVALUATION OF ANDEAN ANCESTRAL KNOWLEDGE ON MEDICINAL HERBS THROUGH THE DEVELOPMENT OF A PHYTOTHERAPEUTIC PRODUCTFrom1 Sep 2023 → TodayFunding: VLIR-UOS Short Training Schorlarships
- Achiral and chiral targeted brain metabolomics in volume-limited samples: quest for broad coverage, sensitivity and throughput using chemical derivatization and miniaturized liquid chromatography tandem mass spectrometry.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Combination of Molecular Dynamics and Quantitative Structure Enantioselective Relationships (QSER) models to elucidate enantiorecognition mechanisms on polysaccharide and antibiotic based chiral selectorsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Modern chiral separation strategies: a tool to facilitate the development of QSRR modelsFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- advanced Metabolomics Platform consisting of two complementary LC-MS/MS analyzersFrom1 May 2016 → 30 Apr 2020Funding: Hercules - Small and Medium size research infrastructure
- Fast metabolite profiles and their data analysis for the prospective study and quality control of plants of pharmaceutical interestFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- ULB-VUB Joint Research Group: Brussels (Bio)Pharmaceutical Analysis Research Group - BBRGFrom5 Nov 2014 → 3 Dec 2022Funding: University - Project driven research
- Chemometrics and metabolite profiles for the prospective study and quality control of plants of pharmaceutical interest: bringing this untapped approach into the fieldFrom1 Sep 2013 → 31 Aug 2016Funding: FWO research project (including WEAVE projects)
- Design space approach for the validation of an innovative continuous pharmaceutical production process.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- Support Vector Machines in Pharmaceutical AnalysisFrom1 Feb 2011 → 31 Jan 2012Funding: FWO visiting post-doctoral fellowship
Publications
41 - 50 of 168
- A comparative study of UniSpray and electrospray sources for the ionization of neuropeptides in liquid chromatography tandem mass spectrometry.(2020)
Authors: Jana Bongaerts, Karen Segers, Laurence Van Oudenhove, Yannick Van Wanseele, Marijn Van Hulle, Dimitri De Bundel, Debby Mangelings, Ilse Smolders, Yvan Vander Heyden, Ann Van Eeckhaut
- Defining a system suitability limit to decide on column deterioration and to facilitate column transfers in chiral supercritical fluid chromatography(2020)
Authors: Sven Declerck, Yvan Vander Heyden, Debby Mangelings
Pages: 6221-6230 - Stationary-phase optimized selectivity in supercritical fluid chromatography using a customized Phase OPtimized Liquid Chromatography kit(2020)
Authors: Yasmine Grooten, Petra Riasová, Inês Salsinha, Debby Mangelings, Yvan Vander Heyden
Pages: 6553-6565 - Three promising antimycobacterial medicinal plants reviewed as potential sources of drug hit candidates against multidrug-resistant tuberculosis(2020)
Authors: Naasson Tuyiringire, Serawit Deyno, Anke Weisheit, Casim Umba Tolo, Deusdedit Tusubira, Jean-Pierre Munyampundu, Patrick Engeu Ogwang, Claude Mambo Muvunyi, Yvan Vander Heyden
- Rendering A Chiral Screening Step In Supercritical Fluid Chromatography Mass-Spectrometry Compatible.(2020)
Authors: Sven Declerck, Yvan Vander Heyden, Debby Mangelings
- Application of Rank Annihilation Factor Analysis for Antibacterial Drugs Determination by Means of pH Gradual Change-UV Spectral Data(2020)
Authors: Mahnaz Esteki, Elham Dashtaki, Yvan Vander Heyden, Jesus Simal-Gandara
Pages: 1-18 - Direct profiling of endogenous metabolites in rat brain microdialysis samples by capillary electrophoresis-mass spectrometry with on-line preconcentration.(2020)
Authors: Marlien van Mever, Karen Segers, Nicolas Drouin, Faisa Guled, Yvan Vander Heyden, Ann Van Eeckhaut, Thomas Hankemeier, Rawi Ramautar
- Evaluation of data preprocessings for the comparison of GC-MS chemical profiles of seized cannabis samples(2020)
Authors: Amorn Slosse, F. Van Durme, N Samyn, Debby Mangelings, Yvan Vander Heyden
- Bioactive Azepine-Indole Alkaloids from Psychotria nemorosa(2020)
Authors: Luiz C Klein-Junior, Sylvian Cretton, Yvan Vander Heyden, André L. Gasper, Samad Nejad-Ebrahimi, Philippe Christen, Amélia T. Henriques
Pages: 852-863 - Detection of adulteration in Chinese monofloral honey using 1H nuclear magnetic resonance and chemometrics.(2020)
Authors: Xiaoying Song, Seng She, Manman Xin, Lei Chen, Yi Li, Yvan Vander Heyden, Karyne M. Rogers, Lanzhen Chen