Name "Responsible (Organisation)" "Activity (Organisation)" "Affiliation (Researcher)" "Quantum Chemistry and Physical Chemistry" "Daniel Escudero Masa" "The methods of quantum mechanics are applied to the study of a wide variety of organic, biological and inorganic compounds. Molecular structure, reactivity and properties are predicted on the basis of theoretical calculations. Due to constant improvements in computer power, and to more and more efficient algorithms, the predictions that can be made are frequently competitive in terms of accuracy with experimental measurements. Computations also provide additional insight into the experimental observations. " "Department of Organic and Macromolecular Chemistry" "Peter Dubruel" "The Department of Organic and Macromolecular Chemistry consists of 8 different research groups divided over 3 main clusters:(Bio)-Organic SynthesisOrganic Analytical MethodsMacro- and Supramolecular Chemistry" "General and Organic Chemistry" "The department AOSC mainly develops research in the areas of: 1. Organometallic Chemistry: Synthesis and characterisation of organotin compounds with potential anti-cancer activity. Structure determination (M. Gielen); 2. High Resolution Nuclear Magnetic Resonance Synthesis and characterisation of organotin polymers for applications in anion recognition and catalysis through advanced structure elucidation by multinuclear and multidimensional NMR spectroscopy (R. Willem & M. Biesemans)." "Analytical Chemistry and Pharmaceutical Technology" "The department consists of two research groups. The main subject of the first (Analytical chemistry) is chemometrics, the application of mathematical and statistical methods to chemical data. This includes both fundamental and more applied work. The fundamental work involves for instance the development of more robust neural networks, variable selection in conjunction with partial least squares or wavelet signal processing that can be applied to sets of spectra instead of to single spectra. The applications, often carried out in collaboration with consortium of industries, such as Glaxo-Wellcome, Novartis, Unilever and Shell to name only a few, concern the online analysis of processes, algorithms for autonomic recognition of excipients with near infra red data, multivariate calibration methods for the determination of octane numbers or the content of active substances in pharmaceuticals, purity analysis of pharmaceuticals, experimental design to speed up the upscaling of granulation processes, schemes for comparing and validating two analysis methods, etc. Additionally, separation methods in pharmaceutical analysis are studied. For instance, a knowledge based method for the selection and optimisation of separation methods for chiral drugs is developed. The second research group concerns Pharmaceutical technology: the subject is the development of different pharmaceutical forms and the investigation of the important parameters involved using optimisation techniques (tableting, sustained release, coating, liposomes, dissolution, chemical stability)." "Department of Clinical chemistry, microbiology and immunology" "The department performs the following research activities: Protein chemistry: projects, among other things, around haptoglobin Center for vaccinology Center for Immunological Basic Research Projects on reproductive endocrinology and aging, calcium and bone metabolism Joint projects of all departments of the laboratory on hematology, bacteriology and virology at the Center for molecular diagnostics (CMD) Projects on multidrug resistance and other forms of therapy resistance in hematological disorders" "Department of Chemistry - other" "This is the general department research group of the Department of Chemisty." "Department of Chemistry" "Jeremy Harvey" "For more information about the research topics of the different research teams belonging to this department see: - Division for biochemistry - Division for fotochemistry and spectroscopy - Division for quantum chemistry - Division for physical and analytical chemistry - Division for organic synthesis - Division for chemical and biological dynamics - Division for coordination chemistry - Division for polymer chemistry" "Materials Chemistry" "Peter ADRIAENSENS" "The research group ""Materials Chemistry"" (MATCHEM) focuses on the synthesis, characterization and application of advanced functional materials. The group encompasses several expertise groups with specific and complementary expertise, closely collaborating and operating within the spearhead research domains of the Institute for Materials Research (IMO) of Hasselt University. The group is also linked to the IMEC associated laboratory 'IMOMEC'. Main activities focus onnew materials for energy generation and energy storage;life sciences materials;materials obtained from waste recycling. The group regularly acts as partner in different European, Flemish, national and international research programs and networks and has a longstanding tradition in joint research and servicing with industry and research centers.Detailed information about the activities of the MATCHEM research group can be found on the imo-imomec website as well as on the EnergyVille website.The expertise groups within MATCHEM are:Design & Synthesis of Organic Semiconductors (DSOS): Prof. dr. Wouter Maes.The key competence of the group relates to the design, synthesis and (structural and optoelectronic) characterization of advanced organic semiconducting materials (polymers as well as smaller chromophores), with particular emphasis on the rationalization of structure-property relations, and their integration in optoelectronic devices (photovoltaics, photodetectors, light-emitting diodes, transistors, chemo/biosensors, ...) and theragnostic applications for personalized healthcare.Hybrid Materials Design (HyMaD): Prof. dr. Dirk Vanderzande and dr. Laurence Lutsen.The group focuses on the design and synthesis of organic-inorganic hybrid materials with specific electro- optical properties and their application in the fields of solar cells, LEDs and detectors. Particular attention is paid to supramolecular interactions that result in the formation of nano-structured hybrid material systems that exhibit functionality in both the organic and inorganic components.Design and synthesis of inorganic materials (DESINe): Prof. dr. Marlies Van Bael and Prof. dr. An Hardy.The main activity is the study of environmentally friendly, chemical methods for the synthesis of high-tech, nanostructured inorganic materials. Solution based synthesis routes, including aqueous and non-aqueous sol(ution)-gel methods, hydro/solvothermal routes, combustion synthesis, co-precipitation, thermal decomposition synthesis, etc. are created for the preparation of functional inorganic nanomaterials. Historically, the main focus was on superconducting, ferroelectric, piezoelectric, conductive and dielectric metal oxide powders and thin films for applications in nanoelectronics, including memories and sensors, in addition to solar cells. In the last decade, the focus shifted to oxide-, metal-, polyanionic- and sulfide-based materials for energy storage in batteries and energy efficiency.  Most recently, the group's expertise is being put to full use in catalysts in the context of ""power to molecules"". Applications include lithium-ion, sodium-ion and lithium-sulfur batteries, as well as thermochromic windows, CO2 reduction and hydrogen production via photocatalysis, photoelectrochemical routes and electrolysis.Biomolecule Design Group (BDG): Prof. dr. Geert-Jan Graulus, Prof. dr. Peter Adriaensens, and Prof. dr. Wanda Guedens.The key competence of the group relates to the development of in vitro/vivo methods for a unique and site-specific functionalization of proteins.  On the one hand, the research is focussed on the bioorthogonal and uniform conjugation of nanobodies to various constructs that pave the way towards improved biosensor, bioimaging and controlled drug release applications. On the other hand, biomimetic structural proteins are designed to enable the effective transplantation of (stem) cells in tissue engineering applications.Advanced Functional Polymer group (AFP): Prof. dr. Louis Pitet.The AFP group focuses on the theme of sustainable polymer technology, with topics like polymers for health care (e.g. tissue engineering), synthesis of polymers in continuous flow (e.g. for manufacturing complex architectures), and polymer technology for a circular economy (e.g. polyester and polyamide waste stream upcycling). Contemporary synthetic tools are explored in a variety of contexts, pushing the boundaries of polymer technology for improved material properties, efficient synthetic protocols, or designed recyclability. The group strives to establish fundamental structure-property relationships in complex polymer scaffolds for advances in a variety of applications.Analytical and Circular Chemistry (ACC): Prof. dr. Wouter Marchal, Prof. dr. Dries Vandamme, Prof. dr. Peter Adriaensens, and dr. Annelies Sels.The focus of the group lies on the design, development and application of suitable analytical strategies for material characterization in order to unravel advanced structure-functionality relationships by advanced and hyphenated physico-chemical techniques. The analytical toolbox is applied to explore processes relating to circular chemistry, including biomass and waste stream valorisation, green extraction and thermal conversion (pyrolysis), and water purification. In addition, environmental issues such as nanoparticle leaching, outgassing and carbon sequestration are addressed. Nuclear Magnetic Resonance (NMR): Prof. dr. Peter Adriaensens.The group focuses on the quantitative description of the structure, molecular dynamics and phase morphology of (polymer) materials by modern liquid and solid-state NMR spectroscopy and relaxometry experiments in order to elucidate macroscopic material properties. Expertise in NMR-metabolomics is also present and focuses on the search for metabolite markers for early diagnosis and therapy follow-up of (lung) cancer." Chemistry "Frederik Tielens" "Academic education and research in chemistry at the Vrije Universiteit Brussel is provided by the Department of Chemistry (DSCH), which is part of the Faculty of Science and Bioengineering. Our department consists of three research groups: the General Chemistry (ALGC), the Organic Chemistry (ORGC) and the Analytical, Environmental and Geochemistry (AMGC). This structure allows us to offer unique undergraduate and two graduate courses in environmental chemistry, organic chemistry and computational chemistry." "Sustainable Chemistry for Metals and Molecules" "Erik Van der Eycken" "Coordination chemistry aims to study the effect of ligand geometry and nature on the central metal ions. These are transition metals (3d, 4d or 5d), lanthanides (4f) and actinides (5f). The symmetry of coordination mainly determines the electronic structure of the metal ions and influences in this way the spectroscopic, electrochemical, thermodynamic and magnetic properties of the complexes. A lot of applications of coordination compounds are found in lasers, up converters, color television, NMR contrast imaging, NMR shifts, high temperature supermagnets, optical, magnetic or radioactive probes as immuno-assays ... Our group is involved with the study of lanthanides, uranium and rather unusual transition metals (Tc, Rh, Ir,...). We use mainly magneto optical spectroscopy, electrochemistry and radiochemistry. We have a solid theoretical background on ligand field theory. Our equipment is: absorption, fluorescence, magnetic circular dichroism, magnetic circular polarized luminescence, Ram an, IR,... photolysis, nuclear instrumentation. We are also specialised in the synthesis and characterisation of lanthanide-containing liquid crystals (metallomesogens). Research is focused on the synthesis, analysis and structure-activity correlations of analogues of bioactive compounds and of supramolecular structures. Synthesis, functional variation and cycloadditions of 2(1H)pyr azinones, 1,4-oxazinones and pyridopyranones. Development of C-nucleosides, specifically substituted pyridines, piperidines, piperazines and polycyclic analogues with potential antiviral, antitumor, bactericide, fungicide or CNS activity. Conversion of sugar compounds into chiral synthons for heterocycles useful as potential inhibitors of e.g. glycosidases, viral replication.... Synthesis of ion-sensitive fluorescent probes for intracellular applications. New strategies for the synthesis of dendrimers using new functionalised porphyrins, carbazoles, alkyne thiolates. Self-assembly of catenanes and rotaxanes by molecular recognition of thi acrown ethers and Ò-electron acceptors. Synthesis and thermolysis of heterocyclic azides. Mechanistic study of rearrangements of five-membered heterocycles."