Basic (bio-) Medical Sciences Vrije Universiteit Brussel
Basic and applied biomedical research, and biomedical science-based higher education.
Basic and applied biomedical research, and biomedical science-based higher education.
Our team wants to find ways to generate new insulin-producing, glucose-regulated "beta" cells that can be used for transplantation in diabetes patients and ways to regenerate beta cells in the pancreas. We study rodent experimental models as well as human cells. The first aim is based on tissue engineering starting from: 1. Exocrine pancreatic cells: reprogramming of adult exocrine cells to endocrine cells, or transdifferentiation in culture. ...
The laboratory for Cell Genetics (Cytogenetics) studies variation in genotype and phenotype, cell division pathways, cell death and genetic changes relevant for the increase of cancer in human. Genotoxicity tests assess the induction of DNA damage, gene mutations, structural and numerical chromosome aberrations. Their predictivity for cancer induction is supported by international studies relating mutations and activation of cancer related ...
Topic A : assisted fertilization for severe male-factor infertility Infertile couples who cannot be treated by standard in vitro fertilization, a.single spermatozoon is injected by micro-manipulation technique into the oocyte. Factors influencing the success of intracytoplasmatic sperm injection. Topic B : Cryopreservation of oocytes and embryos Since the number of oocytes and embryos which are replaced has to be limited to two or three, ...
The research unit Protein Chemistry (SPRO) goes back to 1967 when it was founded thanks to the joint efforts of Prof. R. Jeener (ULB) and Prof. L. Kanarek, who retired a few years ago. Originally, the research activities focused on the immunogenicity of hen egg white lysozyme and its proteolytic fragments. Since the early seventies, the research topics diversified. Over the years the lab developed original technologies for the purification of ...