Patents

A method for activating an exposed surface (1) of a porous dielectric layer (2), the method comprising the steps of: I. Filling with a first liquid (5) at least the pores (4) present in a part (10) of the porous dielectric layer (2), said part (10) comprising the exposed surface (1), II. Removing the first liquid (5) selectively from the surface (1), III. Activating the exposed surface (1), and IV. Removing the first liquid (5) from the bulk part (3) of the porous dielectric layer (2).

The present invention provides methods for predicting post-operative recurrence of Crohn's disease (CD) in a subject. With the present invention it is possible to predict whether a patient undergoing surgical treatment of CD is at risk of developing histological, radiographic, endoscopic, and/or clinical recurrence of the disease.

The present invention relates to the use of GLO1 to modulate acetic acid tolerance in yeast. More specifically, it relates to the use of a specific GLO1 allele to confer tolerance to acetic acid, and to improve the fermentation performance of yeast in the presence of acetic acid.

The present invention provides a method for analysis of target nucleic acids which are present in low amounts. In particular, the method comprises the following steps: i. providing a sample wherein target nucleic acids are present in a low amount, ii. generating a reduced representation library of said target nucleic acids by a method comprising: ⋅ fragmenting said target nucleic acids; ligating adaptors to said fragments; and selecting a subset of said adaptor-ligated fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said ...

The present invention relates to an EUVL scanner (10). The EUVL scanner comprises: an EUV light source (110); a reticle (120); a pellicle (130) mounted in front of the reticle (120) and comprising an EUV transmissive membrane (132) which, in use, scatters transmitted light into an elliptical scattering pattern (112) having a major axis (114); and an anamorphic high-NA imaging system (140) configured to project, onto a target wafer (150), light reflected by the reticle (120) through the pellicle (130); wherein a cross section (162) of an acceptance cone (160) of the imaging system (140) has a ...

The invention relates to a cell culture medium and the use of such medium for the growth and maintenance of organoids from endometriosis tumor tissue.

Immediate release formulation of a triple combination of active pharmaceutical ingredients useful in the treatment of polycystic ovarysyndrome It relates to an immediate release formulation for oral administration, comprising; a) a combination of three active pharmaceutical ingredients which are spironolactone; pioglitazone or a salt thereof; and metformin or a salt thereof; and b) solid polyethylene glycol having an average molecular weight from 3350 to 8000 g/mol; wherein: each of the active pharmaceutical ingredients are present in a therapeutically effective amount; and the polyethylene ...

The present invention relates to mono- or di-substituted indole compounds, methods to prevent or treat dengue viral infections by using the compounds and also relates to use of the compounds as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation ...

A pedal configured to couple to a pedal spindle along a coupling axis is disclosed. The pedal comprises a pedal surface for application of force by a user and a pedal frame coupled to the surface, the pedal frame supporting a first strain sensor configured to detect strain in a first direction and a second strain sensor configured to detect strain in a second direction substantially perpendicular to the first direction. The first strain sensor is disposed on a first face of the pedal frame, the pedal frame having a first frame thickness at the first face in the first direction. The second ...

A method for the reduction of motion artifacts in CT imaging, the method including the steps of: (a) reconstructing from the raw CT data an initial estimate of the object of interest; (b) estimating the pose of the object at each projection angle; (c) undertaking a motion-corrected reconstruction from the measured projections, accounting for the pose changes estimated in (b) by employing a modified source/detector orbit that accounts for the object motion; (d) iterating steps (b)-(c) until a predetermined convergence criterion is met; and (e) making a final reconstruction of the required ...