Projects
In vivo imaging and therapy using labeled antibody derivatives KU Leuven
Glycans play a central role in numerous events in cell-cell recognition, cell communication and cell mobility. Errors in glycan architecture and expression level can lead to pathologies such as cancer. Tumor Associated Carbohydrate Antigens (TACA) are specific glycans that can serve as biomarkers for tumor diagnostics as is already the case for carcinoembryogenic antigen (CEA). This project will focus on the xeno-glycan Neu5Gc ...
Inorganic sorption materials tailored for 225Ra/225Ac and 225Ac/213Bi radionuclide generators for biomedical applications KU Leuven
Biomedical applications of radionuclides, such as radiotherapy and medical imaging, require pure fractions of a broad range of radionuclides, which is mostly achieved by chromatographic column separation. Solid phases predominantly used in chromatographic separation, such as alumina or organic ion exchange resins and extraction resins suffer from several drawbacks, e.g. limited shelf-life, low sorption capacity and radiolysis. Alternatively, ...
Low-temperature oxidation of fine UO2 powders KU Leuven
Globally the most used nuclear fuel material is uranium(IV) oxide (UO2) and it is produced by powder metallurgical processing. Powders are first compacted into cylindrical pellets, which are subsequently sintered at high temperature to increase their density. The UO2 nuclear fuel cycle is also inseparable from wet-chemical routes: uranium is leached from ore bodies and is further purified via, for example, ion exchange or solvent extraction ...
Parent-offspring conflict in canaries: individual plasticity, genetic basis and co-adaptation. University of Antwerp
Synthesis and biological evaluation of carbon-11 and fluorine-18 labelled P2X7-receptor ligands for diagnosis of neurological diseases using positron emission tomography KU Leuven
Neurodegenerative brain diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis and amyotrophic lateral sclerosis are associated with progressive neuronal cell loss and neuroinflammation. Neuroinflammatory processes can be described as a release of neurotoxic substances which accelerate disease progression. As the incidence of neurodegenerative disorders increases and treatment is in most cases only effective in the ...
UO2 and ThO2 doped nuclear fuel KU Leuven
UO2 and ThO2 Doped Fuel
In the nuclear field, research must advance fast enough to keep pace with the industry’s growing demands and new applications. Safety and high performance needs to be maintained for both fuel and reactor. Major progresses have been made in this matter thanks to the development of a new generation of nuclear fuel.
A wide variety of fission products (FP) are formed during the fission chain ...