The role of psychological factors and central neurotransmitter systems in visceral and somatic pain in health and functional somatic disorders. KU Leuven
Functional Dyspensia (FD) is characterized by chronic/recurrent pain/discomfort in the gastroduodenal region that cannot be explained by structural or biochemical abnormalities. The pathophysiology of FD remains incompletely understood, but consists probably of a complex interaction between biological, psychological and social factors. More specifically, peripheral and/or central sensitization at different levels of the 'brain-gut axis' may play ...