Cross-species applicability of high throughput screening assays for thyroid hormone disruption. University of Antwerp
There is currently an urgent need for new screening approaches to identify thyroid hormone disrupting chemicals, both in ecotoxicology and human toxicology. Toxicity testing in the 21st century increasingly relies on high throughput animal-free assays screening chemicals for their interaction with biological targets. While the thyroid system is highly conserved across vertebrate classes, conservation of the chemical susceptibility of the ...