Exploring viral evolution with respect to disease progression and therapy-response in HCV infection. KU Leuven
Chronic hepatitis caused by the hepatitis C virus is a serious public health problem and affects more than 170 million people worldwide. Infection by HCV is defined by a complex interplay between virus and host. Already from the beginning, both virus and host genetics define the disease progression in a patient, ranging from spontaneous clearance to chronic infection potentially leading to liver cancer. Treatment options are limited, but viral ...