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A public health value-based healthcare paradigm for HIV Vrije Universiteit Brussel Institute of Tropical Medicine KU Leuven

Sebastian Vermeersch, Rémy P Demeester, Nathalie Ausselet, Steven Callens, Paul De Munter, Eric Florence, Jean-Christophe Goffard, Sophie Henrard, Patrick Lacor, Peter Messiaen, et al.

BACKGROUND: HIV patients face considerable acute and chronic healthcare needs and battling the HIV epidemic remains of the utmost importance. By focusing on health outcomes in relation to the cost of care, value-based healthcare (VBHC) proposes a strategy to optimize quality of care and cost-efficiency. Its implementation may provide an answer to the increasing pressure to optimize spending in healthcare while improving patient outcomes. This ...

Anticipating hopes, fears and expectations towards COVID-19 vaccines: A qualitative interview study in seven European countries KU Leuven

Janneke Kuiper, Elisa Lievevrouw, Luca Marelli, Ine Van Hoyweghen
Vaccine uptake is essential to managing the ongoing COVID-19 pandemic, and vaccine hesitancy is a persistent concern. At the same time, both decision-makers and the general population have high hopes for COVID-19 vaccination. Drawing from qualitative interview data collected in October 2020 as part of the pan-European SolPan study, this study explores early and anticipatory expectations, hopes and fears regarding COVID-19 vaccination across ...

Analysis of the COVID-19 pandemic Vrije Universiteit Brussel

Yibeltal Assefa, Charles F Gilks, Simon Reid, Remco van de Pas, Dereje Gedle Gete, Wim Van Damme

BACKGROUND: The pandemic of Coronavirus Disease 2019 (COVID-19) is a timely reminder of the nature and impact of Public Health Emergencies of International Concern. As of 12 January 2022, there were over 314 million cases and over 5.5 million deaths notified since the start of the pandemic. The COVID-19 pandemic takes variable shapes and forms, in terms of cases and deaths, in different regions and countries of the world. The objective of ...

Psychosocial care responses to terrorist attacks Vrije Universiteit Brussel

Lise Eilin Stene, Cécile Vuillermoz, Roel Van Overmeire, Johan Bilsen, Michel Dückers, Lisa Govasli Nilsen, Stéphanie Vandentorren

BACKGROUND: The international terrorism threat urges societies to invest in the planning and organization of psychosocial care. With the aim to contribute to cross-national learning, this study describes the content, target populations and providers of psychosocial care to civilians after terrorist attacks in Norway, France and Belgium.

METHODS: We identified and reviewed pre- and post-attack policy documents, guidelines, reports and ...

Determination of pesticide residues in chilli and Sichuan pepper by high performance liquid chromatography quadrupole time-of-flight mass spectrometry. KU Leuven

Ann Van Schepdael
In this study, a multi-component analytical method for the detection of pesticide residues in chilli and Sichuan pepper by high performance liquid chromatography coupled with quadrupole time of flight mass spectrometry (LC-Q-TOF/MS) was developed and validated. The sample preparation is based on an extraction step with acetonitrile followed by a cleanup step using primary secondary amine, C18, graphitized carbon black and anhydrous magnesium ...

Authentication of extra virgin Argan oil by selected-ion flow-tube mass-spectrometry fingerprinting and chemometrics Vrije Universiteit Brussel

Mourad Kharbach, Huiwen Yu, Rabie Kamal, Ilias Marmouzi, Katim Alaoui, Joeri Vercammen, Abdelaziz Bouklouze, Yvan Vander Heyden

Recognized for its nutritional and therapeutic use, extra-virgin Argan Oil (EVAO) is frequently adulterated. Selected-Ion Flow-Tube Mass Spectrometry (SIFT-MS) spectra were applied to quantify adulterants (i.e., Argan oil of lower quality (LQAO), olive oil (OO), and sunflower oil (SO)) in EVAO. Four data sets, i.e., using H3O+, NO+, O2+ reagent ions, and the combined data were considered. Soft independent modelling of class analogy (SIMCA), ...

Digestion kinetics of lipids and proteins in plant-based shakes: Impact of processing conditions and resulting structural properties KU Leuven

Sarah Verkempinck, Marcos Ricardo Infantes Garcia, Marc Hendrickx, Ann Van Loey, Tara Grauwet
In this work, plant-based shakes were prepared (5% oil, 6% protein, 1% lecithin, 88% water) (w/w) using two processing techniques (i) only mixing versus (ii) mixing followed by high pressure homogenisation, as well as two processing sequences (i) adding all ingredients together versus (ii) stepwise addition of ingredients. Shakes only mixed consisted of large, irregular particles (1–100 µm). Eventually, this resulted in a relatively low lipid ...

Impact of processing on the production of a carotenoid-rich Cucurbita maxima cv. Hokkaido pumpkin juice KU Leuven

Sharmaine Atencio, Sarah Verkempinck, Tom Bernaerts, Marc Hendrickx, Ann Van Loey
Pumpkin juice with high carotenoid content can be attractive natural alternative for artificial food colourants. We evaluated the impact of processing treatments on aqueous carotenoid extraction from pumpkins, aiming to enhance carotenoid transfer into the juice fraction. Crushed whole pumpkins were processed by high pressure homogenization (HPH) for mechanical cell disruption, by enzymatic treatment for cell wall polysaccharide degradation or ...

A review of European guidelines for patient blood management with a particular emphasis on antifibrinolytic drug administration for cardiac surgery. KU Leuven

Steffen Rex
The concept of patient blood management (PBM) was introduced by the World Health Organization in 2011 and is defined as a "patient-focused, evidence-based and systematic approach for optimizing the management of patients and transfusion of blood products to ensure high quality and effective patient care". Patient blood management is a multimodal approach based on three pillars: optimization of blood mass, minimization of blood loss and ...