Combining targeted therapy and chemotherapy in acute lymphoblastic leukemia KU Leuven
Acute lymphoblastic leukemia (ALL) is a hematological disease, which arises from the malignant T or B cell transformation of developing progenitor cells. It is the most common childhood cancer. Despite the increased overall survival and improved risk stratification, relapse and failure to achieve clinical remission remain major challenges. Further intensification of current treatment regimens is not an option due to the already high toxicity, ...