Identification of novel targets for treatment in T-cell acute lymphoblastic leukemia KU Leuven
T-cell acute lymphoblastic leukemia is an aggressive hematological malignancy, characterized by the uncontrolled proliferation of immature lymphocytes in the bone marrow. Though treatment has become highly effective in children, there is still an unmet medical need. In the relapse/refractory setting or for adult patients, treatment outcome and 5-year survival remain poor. Treatment consists of complex and intensive chemotherapy regimens, with ...