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Epithelial label-retaining cells are absent during tooth cycling in Salmo salar and Polypterus senegalus Ghent University
Tooth replacement in an evo-devo context : the dental lamina as a possible source of stem cells Ghent University
The enthralling ability to continuously replace teeth throughout life has fascinated scientists for decades. This ability (polyphyodonty) is maintained in almost all tooth-bearing non-mammalian vertebrates. Teeth are organised in tooth families, i.e. a functional tooth and all of its successors (Reif, 1982). In general, first and later generation teeth develop within an epithelial dental lamina as result of interaction of the epithelial cells ...
Tooth replacement without a dental lamina: the search for epithelial stem cells in Polypterus senegalus Ghent University
Aspects of tooth replacement in a basal actinopterygian, Polypterus senegalus Ghent University
Most actinopterygians replace their teeth continuously throughout life. Major differences are nevertheless observed in the spatial and temporal relationship between a developing replacement tooth and its predecessor. In this study we address the question of where and how replacement teeth form in the African bichir (Polypterus senegalus). Furthermore we test if there is any evidence for the presence of epithelial stem cells, hypothesized to play ...
Dual BrdU-PCNA immunodetection of proliferative cells in dental and orofacial tissues of teleosts Ghent University
The pattern of the lower jaw dentition in farmed Atlantic salmon (Salmo salar): a tool to study mechanisms of tooth replacement? Ghent University
Identification of potential epithelial stem cells responsible for continuous tooth replacement in the African bichir (Polypterus senegalus), a basal Osteichtyan Ghent University
In this thesis we wished to test the hypothesis that stem cells are involved in the process of continuous tooth replacement in the basal actinopterygian, Polypterus senegalus (African bichir). First, we studied the morphology of the dentition and the tooth replacement pattern on the premaxillary, maxillary and dentary, using cleared and alizarin red stained heads of juvenile Polypterus. Each of these bones bears one row of functional teeth. In ...