Publications

The interdisciplinary field of phenomenology and cognitive science is thriving. Recently, it has gained even further ground through the rise of a new cluster of paradigms in philosophy of mind and cognitive science, which can be collectively referred as the model of '4E' cognition. This model takes cognitive processes to be Embodied, Enactive, Embedded, and/or Extended. Those 4E's promise fertile crossovers between analytic and continental ...

The interaction between the eukaryotic translation initiation factor 4E (eIF4E) and eIF4E binding proteins (4E-BP) is a promising template for the inhibition of eIF4E and the treatment of diseases such as cancer and a spectrum of autism disorders, including the Fragile X syndrome (FXS). Here, we report an atomically detailed model of the complex between eIF4E and a peptide fragment of a 4E-BP, the cytoplasmic Fragile X interacting protein ...

Dipeptidyl peptidase 8 (DPP8) and 9 (DPP9) are proteases gaining significant attention for their role in health and disease. Distinctive studies of these proteases are hampered by their close homology. Furthermore, designing selective compounds is a major challenge due to the highly conserved catalytic site. Here, we provide mechanistic insights underlying the DPP9‐over‐DPP8 selectivity of the semi‐selective inhibitor “Compound 42”. We performed ...

© The Author(s) 2015. We study the nuclear ground-state properties by using the unitary-model-operator approach (UMOA). Recently, the particle-basis formalism has been introduced in the UMOA, enabling us to employ the charge-dependent nucleon-nucleon interaction. We evaluate the ground-state energies and charge radii of 4He, 16O, 40Ca, and 56Ni with the charge-dependent Bonn potential. The ground-state energy is dominated by the contributions ...

An organometallic building block strategy was employed to investigate the magnetic properties of a LnIII organometallic single-ion magnet (SIM) and subsequent single-molecule magnet (SMM) after coupling two of the monomeric units. New homoleptic DyIIICOT″2 and LnIII 2COT″3 (Ln = Gd, Dy) complexes have been synthesized. DFT calculations of the bimetallic DyIII complex indicate strong metal−ligand covalency and uneven donation to the DyIII ions by ...

This paper presents a novel design approach for fully reconfigurable low-voltage delta-sigma analog-digital converters for next-generation wireless applications. This approach guides us to find the power-optimal solution corresponding to the specifications of various wireless standards by exploring single-loop feedback and feedforward topologies with different filter order, number of quantizer bits, and oversampling ratios. Unlike previous ...