A Trojan-Horse Strategy for Antimicrobial Therapy KU Leuven
Over the last seven decades, antibiotics have been essential componentsof modern medicines and this is one of the leading causes for our increased life expectancy. However, due to development of resistance to the existing antibiotics, there is an urgent need to look for new analogues or new bacterial targets which are essential for the survival of pathogens. Recently, aminoacyl-tRNA synthetases (aaRSs) have emerged as promising and clinically ...