Study on the role of macrophages in neurodegeneration during aging KU Leuven
Tissue resident macrophages have long been known for their role in host defense and pathogen clearance, but only in recent years have we come to appreciate that these cells can develop a surprising degree of functional specialisation, thereby fulfilling tissue-specific functions in the organ in which they reside. The instruction of such specific functions is largely imprinted via signalling from surrounding cells, the so-called macrophages ...