Projects
Image-guided decoding of mechanisms involved in healthy, accelerated and pathological aging. University of Antwerp
Sub-Saharan African migrant women living and aging with HIV/AIDS in Belgium: challenges and resilience Vrije Universiteit Brussel
2. To identify the coping strategies employed by these women to live a good quality life and age well with HIV/AIDS.
The aging brain in action: towards a multi-modal imaging approach of motor control. KU Leuven
The aging population poses unprecedented challenges for society. Here, we will investigate age-related changes in the brain in relation to movement control. The basic premise is that age-related decreases in motor performance are associated with functional and structural changes in the brain. To achieve this goal, we will use a complementary multimodal imaging approach consisting of magnetic resonance imaging (MRI), electroencephalography ...
Interhemispheric interactions in the aging brain and their tructural modulation with training-induced europlasticity. KU Leuven
In the rapidly aging society, functional independence of these aging adults is a substantial issue in terms of health and well-being at both the individual and society level, as well as from an economic perspective. The structural and functional changes in the aging brain are associated with a decline in movement control, a prerequisite for functional independence. The proposed project utilises a unique multi-modal approach, which enables us ...
Identification of new effectors of the protein kinases Pho85 and Sch9, involved in the aging of the yeast Saccharomyces cerevisiae. KU Leuven
This project focuses on a further elucidation of the role of the yeast protein kinase Sch9 in the nutrientinduced signalling network. We will do this by focusing on specific results obtained in our lab, as well as searching for novel Sch9 functions and targets on a genome-wide scale. Furthermore, a detailed functional analysis will be performed of the lipid-binding C2 domain contained within the Sch9 protein.
Sex hormone binding globulin in men: the free hormone hypothesis revisited during aging and endocrine disorders KU Leuven
Sex hormones (with testosterone as main male sex hormone) belong to the family of steroid hormones. Only the ‘free’ (unbound) fraction is active, but in the circulation these hormones are mainly bound to proteins, with sex hormone binding globulin (SHBG) as most important player. Concentrations of SHBG and thus biological availability of sex steroids change considerably, not only during disease but also during aging. Moreover, the assessment ...