Using molecular signaling profile in white blood cells measured by highly-sensitive mass spectrometry (MS)-based proteomics in the differential diagnosis between major depressive disorder and bipolar disorder. University of Antwerp
Major depressive disorder (MDD) and bipolar spectrum disorder (BD) are severely debilitating mental disorders both characterized by an elaborate depressive symptomatology. In clinical reality, patients with either unipolar or bipolar depression often present with identical symptoms, resulting in a profile of clinically observable symptomatology that in itself remains insufficient for reliable and objective distinction and consequent correct ...