High pressure intraperitoneal aerosolization of chemotherapeutics, nanoparticles and hydrogels to treat peritoneal carcinomatosis: effect on tumor penetration, biodistribution and anti-cancer activity. Ghent University
Yearly, about 150000 people develop peritoneal carcinomatosis (PC) in Europe alone. PC is
characterized by the spread of numerous small tumor nodules in the peritoneal cavity. After initial
surgery, where as many tumor nodules are removed as possible, the patients receive the
intraperitoneal injection of chemotherapeutics such as cisplatin. The prognosis of this patients is
however poor, with a median survival of 8 to ...