Projects
Integrating a novel layer of synthetic biology tools in Pseudomonas, inspired by bacterial viruses KU Leuven
As nature’s first bioengineers, bacteriophages have evolved to modify, adapt and control their bacterial hosts through billions of years of interactions. Indeed, like modern synthetic biologists aspire to do, bacteriophages already evade bacterial silencing of their xenogeneic DNA, subvert host gene expression, and co-opt both the central and peripheral metabolisms of their hosts. Studying these key insights from a molecular systems biology ...
Cell-PHactory: Exploiting phage as a source of novel synthetic biology tools to improve industrial fermentations. KU Leuven
As nature’s first bioengineers, bacteriophage have evolved to modify, adapt and control their bacterial hosts through billions of years of interactions. Indeed, like modern synthetic biologists aspire to do, bacteriophages already evade bacterial silencing of their xenogeneic DNA, subvert host gene expression, and co-opt both the central and peripheral host metabolisms of their hosts. Studying these key insights from a molecular systems ...
Bioframe, a bioinformatics framework for top down systems biology Ghent University
Systems biology can be defined as the study of biological systems as complex systems arising from interactions between its multiple components. The bioframe project aims at the design of an algorithmic platform for the integration of coupled expression or interaction datasets, pragmatic and useful for the biologist, highly integrated and flexible.