Projects
New types of nanophotonic biosensors on silicon-on-insulator Ghent University
In this PhD project we will research novel types of nanophotonic biosensors, with special emphasis on obtaining low detection limit.
Development of synthetic routes towards new architectures for conjugated polymers for application in solar cells and biosensors. Hasselt University
Nanolasers in indiumphosphide membranes for optical signal processing and biosensors Ghent University
In this project, basic research will be performed into nanolasers based on photonic crystals in an indium phosphide (InP) membrane bonded to silicon. We will investigate two applications of this device: on one hand as basic component in a flip-flop for all-optical signal processing, on the other hand as extremely sensitive biosensor.
Compact nanophotonic biosensors leveraging integrated sources and detectors KU Leuven
Optical instrumentation has a key role in life science research and diagnostics. Optical techniques based on fluorescence, absorption, spectroscopy, microscopy etc. are routinely used in the clinical practice. For reasons of performance, cost and form factor, free space optics is recently increasingly replaced by integrated photonics, which allows to integrate a wide variety of optical functionality on a small chip, lowering cost and ...
Tailoring surface properties for life science applications - Atomic and Molecular Layer Deposition for the conformal coating of biosensors Ghent University
Liquid based techniques are widely used for the surface functionalization of biosensors, e.g. to produce protein-resistant (i.e. antifouling) coatings or to covalently and site-specifically bind biomolecules. A major problem associated with solution-based coatings, concerns incomplete wetting of high aspect ratio structures, e.g. when trying to functionalize the interior surface of microfluidic channels. In this project, we propose to explore ...
Label-free Biosensors based on polymer photonic microrings working in visible wavelenght and their applications Ghent University
Use of biosensors for necrotic cell death Ghent University
This project implies a fundamental research program on the molecular mechanisms of necrotic cell death and the development of cellular reporter systems for carbohydrate metabolism and RIP1/RIP3 activation for RNAi and small compound library screening. As such, this platform becomes a powerful tool to identify critical nodes of the signaling network and markers for necrosis with potential diagnostic, prognostic and therapeutic use in ...
Construction and implementation of a versatile high-throughput platform for development of fluorescent protein based biosensors. KU Leuven
A profound insight into life can only be obtained by studying living systems with high spatiotemporal resolution. Until now, the most powerful method for doing this is light microscopy. Light microscopy allows us to study living systems, be it cells or complete organisms, with a submicrometer spatial and subsecond temporal resolution. To study specific molecules or reactions amidst the multitude of processes going on, one typically labels one ...
True colors are shining through: Flow cytometric biosensors as a new concept in forensic toxicology Ghent University
Over the last decade, new psychoactive substances (NPS) have been flooding the drug market. The
continuously changing chemistry of these substances -aiming at generating substances with
increased potency and at avoiding legislation- poses a major challenge for current detection
techniques, which are mainly based on the chemical structure of the NPS. Immunoassays only
recognize a very limited set of compounds, while ...