Projects
Biomarkers affecting the transition from cardiovascular disease to lung cancer: towards stratified interception. KU Leuven
Cardiovascular disease (CVD) and lung cancer (LC) are leading causes of deaths and intertwined chronic inflammatory processes associated with metabolism reprogramming, clonal hematopoiesis of indeterminate potential (CHIP), intestinal dysbiosis, and maladaptive immunity. CVD prone-tobacco users exhibit a 1-2% yearly incidence of LC. Low dose computed tomography screening programs reduce LC mortality by 20%. Beyond epidemiological scores, risk ...
Integrated silicon photonics for Cardiovascular Disease monitoring Ghent University
The rationale for Medtronic and partners to propose the InSiDe project is the unmet need of the medical community for reliable, non-invasive, cheap and easy-to-use tools able to identify and characterize different stages of cardiovascular diseases. Solving this need ensures the early adoption of the appropriate therapies, dramatically reduces healthcare costs and importantly, improves patient outcome. In fact, monitoring arterial stiffness by ...
Tissue-specific induction of autophagy as an innovative therapeutic strategy in cardiovascular and metabolic disease. (CARDIOPHAGY). University of Antwerp
CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease Vrije Universiteit Brussel
WHO estimates 17.7 million people die each year from cardiovascular disease (CVD), an estimated 31% of all deaths worldwide. While progress with conventional treatments is making incremental gains, there remains a need to develop innovative therapeutic approaches. Gene therapy has gained significant momentum, mainly for treatment of rare monogenetic diseases. Marketing authorization for gene therapy products has not impacted ...
Use of Microorganisms for Carotenoids Delivery: Next Generation of Probiotics for Cardiovascular Disease Ghent University
CARODEL aims to valorise the result from the previous FP7 COLORSPORE, project, in which initial isolation and characterization work was performed on Bacillus strains producing gastric-stable carotenolds. As the stability in the gastrointestinal Iract (GIT), antioxidant activity and biosavailability of particular Bacillus carotenoids was shown to be higher than those of common dietary carotenoids, the conclusions from COLORSPORE provided ...
Joint Action on Cardiovascular Diseases and Diabetes (JACARDI). University of Antwerp
RADical reduction of OXidative stress in cardiovascular diseases. KU Leuven
Cardiovascular disease (CVD) constitutes a major and increasing health burden in developed countries. The prediction is that the prevalence of these conditions will increase by ~60% over the next 20 years. Therefore, the development of novel treatments for patients with CVD becomes more and more urgent. Oxidative stress is an important molecular contributor to the pathogenesis of CVD. However, oxidative stress-related therapeutic strategies ...
Production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases. Vrije Universiteit Brussel
JACARDI Joint Action on CARdiovascular Diseases and DIabetes KU Leuven
The JACARDI project aligns with the objectives of the European Union Health Programme (EU4H) by focusing on the reduction of NCDs at both individual and societal levels. It seeks to reduce the burden of CVD and DM while increasing awareness of related risks and the acceptance of innovative lifestyle interventions.
The project’s relevance extends to addressing the diverse needs of the people in Europe, harmonizing health systems, and ...