Projects
Identifying (psycho)physiology-based subgroups in chronic fatigue syndrome and their relevance for rehabilitation KU Leuven
About 20 000 people in Belgium suffer from Chronic Fatigue Syndrome (CFS), a disorder characterized by persisting fatigue insufficiently explained by known medical or psychiatric conditions. Dysfunction of several (psycho)physiological systems, such as the stress response system (including the hypothalamo-pituitary-adrenal axis and the autonomic nervous system), the immune system (systemic inflammation), and the central nervous system ...
Dynamic monitoring and risk assessment of chronic fatigue in survivors of childhood cancer. KU Leuven
As survival rates have increased tremendously in children and
adolescents treated for cancer, the long-term sequelae of the
childhood cancer treatment play an increasingly important role in
their daily life quality. A frequently experienced symptom is a chronic
feeling of fatigue, of which the prevalence reaches up to 85% in
childhood cancer survivors.
Although this has a large negative impact ...
Early adversity, self-critical perfectionism and epigenetic mechanisms in Chronic Fatigue Syndrome. KU Leuven
There is increasing evidence that Chronic Fatigue Syndrome (CFS), a highly debilitating disorder characterized by unexplained persistent fatigue, reflects a ‘crash’ of the human stress response system responsible for the production of the hormone cortisol which enables an individual to adapt to stress. We have demonstrated that this loss of resilience of the stress system in CFS may result from chronic stress related to a history of early ...
Assessment of personality dimensions and clinical subtypes in Chronic Fatigue Syndrome and their predictive value for the (long-term) outcomes after group cognitive behaviour therapy. University of Antwerp
Understanding mitochondrial function and the role of exogenous ketone supplementation in combating exercise intolerance and chronic fatigue in long COVID. Vrije Universiteit Brussel
term effects (long COVID). The symptoms (mostly fatigue and postexertional symptom exacerbation (PESE)) influence the life of these
patients. The current guidelines for rehabilitation are insufficient and
the pathogenesis is not fully understood. The first aim is to
understand the role of mitochondrial function (MF) in long COVID,
using a ...
Fatigue and Stroke Recovery (FaStR): Trajectories of Sleep, Physical Activity & Inflammation as Potential Mediators. A Longitudinal Cohort Study. Vrije Universiteit Brussel
Impact of an intensive rehabilitation programme integrating advanced rehabilitation technology for adults in the chronic phase after a stroke: A randomised controlled trial. KU Leuven
The doctoral research consists of a four-year project. The overall aim of this project is to gain knowledge about the effectiveness of an intensive rehabilitation programme using advanced technology in adults with neurological disorders in the chronic phase. This project consists of data collection and analysis of a pilot study (1) and a large phase III randomised controlled trial (2).
(1) The pilot study was conducted in 2022 and had ...
AsthenesLAB KU Leuven
Aversive bodily sensations such as pain, breathlessness and tinnitus are very common. Initially, they serve an important protective function by motivating behaviors that support recovery and healing. However, when these sensations persist and turn into chronic bodily symptoms, they cease to be protective, and elicit significant suffering, disability, and costs. The interdisciplinary ASTHENES research program aims at improving our ...