Profiling (sub)clonal architecture and phylogeny in tumors by novel techniques for whole-genome sequence data mining and single-cell genome sequencing. KU Leuven
A normal human individual has 23 pairs of chromosomes (collectively called the genome) in nearly all of its living cells. In the early 21st century, the sequence of the human genome has been determined, after a 15-year massive international effort. Cancers develop due to accumulated errors in the genome, leading to a cell whose growth can no longer be kept in check and that develops into a mass of cells that endangers the organism. The genomes ...