Projects
Self-criticism and affective spectrum symptoms during adolescence: The role of the parenting environment, genetic vulnerability, and their interaction KU Leuven
Studies have shown that depression and functional somatic disorders (e.g., chronic pain and fatigue conditions) are highly comorbid and tend to co-aggregate within families. Hence, researchers argue that depression and functional somatic disorders belong to an “affective spectrum” of disorders that possibly share etiological mechanisms. A growing body of research suggests that self-criticism (i.e., a personality dimension marked by high ...
PAVING THE ROAD FOR PRECISION MEDICINE: THE ROLE OF STRESS MONITORING AND INFLAMMATION IN DEPRESSION KU Leuven
Major Depressive Disorder (MDD), in many patients, takes the form of a chronic, relapsing-remitting disorder. During past decades, it has become clear that biological changes may underlie MDD (1) . These changes do not only suggest a biological base of mood disorders, but may also be used as tool to predict response and relapse and can hence provide valuable information as to the selection of adequate treatment for patients with MDD.
One ...
Too puzzled to progress: Identity formation as a key developmental process and a central issue within personality pathology in community and clinical samples KU Leuven
Identity formation is a key developmental process that unfolds across the lifespan. Especially during adolescence and emerging adulthood, young individuals search for a (new) sense of coherence and continuity, which enables them to move through life with purpose, and experience feelings of personal meaning and well-being. Problems associated with identity formation are considered a core symptom of personality pathology. Consequently, the ...
Humanizing questions. Exploration of the existential dimension in psychiatry through research on demoralization in patients with schizophrenia KU Leuven
Humanizing questions. Exploration of the existential dimension in psychiatry through research on demoralization in patients with schizophrenia.
(Doctoral thesis offered to obtain the degree of Doctor of Psychological Sciences, 2019). Supervisors: Prof. dr. Jozef Corveleyn and Prof. dr. Bernard Sabbe (UAntwerp). Co-supervisor: Prof. dr. Patrick Luyten.
Background In patients with a severe psychiatric disorder, it is not ...
Unravelling the pathophysiology of psychotic depression: the search for peripheral and endophenotypical biomarkers. University of Antwerp
Neurobiology of psychomotor symptoms in late life depression KU Leuven
Depression is the most common cause of years lived with disability in Europe and ranked in the top ten causes of impaired health worldwide. Primary a disorder of mood, depression is also associated with cognitive and motor disturbances. Psychomotor disturbance (PMD), a collective term for both slowing (retardation) and increased motor activity (agitation), is encountered in 20 - 60% of patients with major depressive disorder (MDD). It ...
The human dog: the effects of accelerated HF-rTMS on functional connectivity and the serotonergic system. A translational canine model. Ghent University
This project proposal concerns the use of the dog as a natural animal model for research on the
effects of a treatment used in human psychiatry that modulates the brain function in regions that
are deficient in human depression and anxiety disorders. The problem with these diseases is that
treatment outcome with classical modalities is suboptimal. Alternative treatments involve noninvasive
...