Projects
Non-Amyloid Pathological Brain Aging in Late Life Depression KU Leuven
Depression and age-related brain disorders such as dementia are together one of the greatest public health issues of our time. With a rapidly increasing aging population and longer life expectancy, the burden associated with depression in later life will only increase. Understanding the neurobiological mechanisms underlying depression is crucial for limiting the personal and economic impact of the disorder by improving diagnosis and ...
Predictive enrichment strategies for immune-targeted interventions in depression. University of Antwerp
The Leuven Student Microbiome Project – a longitudinal analysis of gut microbiome predictors of depression and suicidality KU Leuven
Priming stimulation: a multimodal approach to evaluate the effects of theta-burst transcranial magnetic stimulation priming on prefrontal cortex functioning in healthy and depressed individuals Ghent University
Intermittent theta-burst stimulation (iTBS) has been increasingly used to target prefrontal brain regions, such as the dorsolateral prefrontal cortex (DLPFC), to optimize therapeutic outcomes in patients suffering from major depressive disorder. However, despite the promising outcomes, clinical efficacy remains rather modest. Interestingly, fundamental research targeting the motor cortex has suggested the use of priming techniques to enhance ...
BINGE EATING AND PURGING IN COLLEGE STUDENTS: CROSS-SECTIONAL AND LONGITUDINAL MULTIVARIATE CORRELATES KU Leuven
INTRODUCTION AND BACKGROUND Binge eating and purging behaviors (BPB) are symptomatic behaviors which can be present in eating disorders and other mental disorders, as well as in non-pathological conditions. Specifically, binge eating refers to episodes during which a person rapidly consumes an excessive quantity of food while feeling a sense of loss of control; purging behaviors are inappropriate compensatory behaviors, aiming to prevent ...
CHaT - Changing Tactics? Changing treatment technique in case of early nonresponse during ECT for major depression: a randomized trial. KU Leuven
Major depressive disorder (MDD) affects one in six adults in their lifetime and imposes a considerable burden of disease on the patient. Despite the widespread use of antidepressant medication, after several treatment steps, at least a third of patients will fail to achieve remission. For patients with so-called difficult-to-treat depression, not responding to several augmentation or combination attempts, electroconvulsive therapy (ECT) has ...
Objectifying Assessment of Human Emotional Processing and Expression of Clinical and Psychotherapy Applications (EMO-App) Vrije Universiteit Brussel
Self-management education for patients with bipolar disorder KU Leuven
Introduction and background
Bipolar disorder (BD) is a severe chronic mental illness characterised by fluctuating mood and activity patterns, alternating between euthymic, hypo-manic or manic, major depressive, and mixed-mood episodes. The diagnosis can be classified according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders as a bipolar I disorder when a service user endures at least one manic ...
Focused Ultrasound Personalized Therapy for the Treatment of Depression Ghent University
Major depressive disorder (MDD) is a mood disorder which can interfere with daily life, and it is a major contributor to the overall global disease burden. About one third of MDD patients do not respond to established treatments. What is more, reliable biomarkers for depression are needed as a diagnostic tool. The EU-funded UPSIDE project aims to address these issues. To that end, it will research and validate in vivo a hybrid neurotechnology ...