Projects
The beta-cell and the immune system in type 1 diabetes: partners in crime - developing new therapies in type 1 diabetes through better understanding of beta-cell behaviour and use of novel immunomodulators. KU Leuven
The beta-cell and the immune system in type 1 diabetes: partners in crime - developing new therapies in type 1 diabetes through better understanding of beta-cell behaviour and use of novel immunomodulators. KU Leuven
Closed-loop insulin delivery in pregnant women with type 1 diabetes (the CRISTAL study) KU Leuven
Type 1 diabetes (T1DM) during pregnancy is associated with increased risk of maternal and neonatal complications such as pre-eclampsia, preterm delivery, caesarean sections, congenital malformations and perinatal mortality. Even with increasing use of new continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII, insulin pumps) technologies, pregnant women with T1DM continue to spend on average 8 hours/day ...
Boosting beta-cell function for treatment of type 1 diabetes KU Leuven
In type 1 diabetic (T1D) patients the pancreatic insulin-producing beta cells are selective destroyed by the immune system, leading to an impaired glucose metabolism. The steep increase in the incidence of this chronic autoimmune pathology especially in young children in the last decades raises serious concerns. To date, insulin therapy is considered the gold standard for the treatment of T1D. Nevertheless, limitations persist, such as the ...
Innovative strategies for screening, diagnosis and prevention of type 1 diabetes. KU Leuven
Biologic Platform for Early Detection, Prevention and Treatment of Type 1 Diabetes Vrije Universiteit Brussel
Breath analysis as a non-invasive biomarker for the early detection of preclinical type 1 diabetes. University of Antwerp
Elucidating the contribution of NAFLD (non-alcoholic fatty liver disease) and insulin resistance in the development of cardiovascular complications in people with type 1 diabetes. University of Antwerp
Influence of glycemic variability on autonomic and cardiovascular function, and its modulation by postprandial exercise training in patients with diabetes type 1 Ghent University
Type 1 diabetes is characterized by chronic hyperglycemia and by acute glycemic fluctuations. The role of this glycemic variability (GV) in the development of diabetic complications is subject of debate. In this study we want to evaluate the impact of GV on autonomic function and vascular complications, as well as to investigate the effects of postprandial exercise on these parameters.