Publications
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Dermatophytic infection by Anixiopsis stercoraria in a wild boar (Sus scrofa) Institute of Tropical Medicine
A 'ring in ring' skin infection in a returning traveller Institute of Tropical Medicine
A 40-year-old woman developed an itchy, expanding cutaneous lesion with two erythematous rings after visiting Senegal. Fungal culture revealed Microsporum audouinii, a fungus causing tinea corporis or capitis commonly in Africa but increasingly reported in outbreaks in Europe.
Microsporum gypseum infection in a horse with severe sweet itch Ghent University
In a horse with severe sweet itch and a history of corticosteroid treatment for this disorder, a single, well-circumscribed and crusty white lesion was present on the thigh. The geophilic dermatophyte species M. gypseum was cultured from the lesion. The lesion was treated topically once a week with an enilconazole emulsion for four weeks. Full recovery was noted after two months. This case suggests that sweet itch combined with systemic ...
Clinical Forms of Dermatophytosis (Ringworm Infection) KU Leuven
Dermatophytic infections of the skin, hairs and nails are very common and are very variable in aspect. In skin, inflammatory symptoms are often absent, but in other cases they may be very pronounced, in particular when caused by zoophilic dermatophytes. In onychomycosis, it is very difficult to make the differential diagnosis with other causes of onychodystrophy on purely clinical grounds; indeed, even in case of fungal infection, the causative ...
Epidemiology of Dermatophytes in Belgium: A 5 Years' Survey. KU Leuven
Dermatophytes are among the most common fungal agents causing superficial skin infections worldwide. Epidemiology of these infections is evolving and variable in every country. This report presents the Belgian epidemiological data regarding the distribution of dermatophytes species isolated by the two national reference centers for mycosis during a period of 5 years (2012-2016). Trichophyton rubrum was the most frequently isolated species, ...
Infrared spectroscopy as a novel tool to diagnose onychomycosis Ghent University
Background: The determination of causative organisms of onychomycosis is still not optimal. There remains a need for a cheap, fast and easy-to-perform diagnostic tool with a high capacity to distinguish between organisms. Objectives: To determine whether attenuated total-reflectance Fourier transform infrared (ATR-FTIR) spectroscopy can detect and differentiate causative agents in culture-based, ex vivo nail and in vivo nail models. Methods: A ...
Culture sur terre et sur milieux à base de terre, de cheveux, de poils, de squames et d'ongles infectés par des dermatophytes Institute of Tropical Medicine
Validation of a New Web Application for Identification of Fungi by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Vrije Universiteit Brussel
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry has emerged as a reliable technique to identify molds involved in human diseases, including dermatophytes, provided that exhaustive reference databases are available. This study assessed an online identification application based on original algorithms and an extensive in-house reference database comprising 11,851 spectra (938 fungal species and 246 ...
Fast and Accurate Identification of Dermatophytes by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry: Validation in the Clinical Laboratory Vrije Universiteit Brussel
The performance of a matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) workflow using an extensive reference database for dermatophyte identification was evaluated on 176 clinical strains. Using a direct-deposit procedure after 3 incubation days yielded 40% correct identification. Both increasing incubation time and using an extraction procedure resulted in 100% correct identification.