Combined transcriptomic and electrophysiological spatiotemporal profiling of neural circuits with a high-density multi-electrode array chip KU Leuven
Studying cellular networks such as neural circuits on a single cell level is essential in understanding complex disorders such as neurodegenerative diseases. Since the dawn of next-generation sequencing technologies and the power of stem cell engineering, it is now feasible to reveal the transcriptomic profile of thousands of cells from patients with poorly understood conditions. On the other hand, neural circuits, even in (simplified) ...