Patient-centered Targeting of Epigenetic Vulnerabilities in Neurodevelopmental Disorders: A Cross-disciplinary Platform for Druggable Disease Models KU Leuven
Intellectual disability disorders (IDDs) represent a spectrum of neurodevelopmental disorders characterized by early childhood onset of learning impairment behavior defects. IDDs are linked to detrimental factors that affect cortical development. Many mutations that cause IDDs have been identified. They represent pathways linked to synaptic function and epigenetic gene-expression control Since epigenetic gene-expression is a key process ...