Laboratory for Signal Integration in Cell Fate Decision KU Leuven
Our scientific interests are to reveal how membrane-associated scaffold proteins and lipids participate in cell signaling and multicellular organization/homeostasis. We provided major contributions to our understanding of the importance of membrane trafficking for the biology of heparan sulfate proteoglycans, the role of phospholipids in the function of PDZ proteins and more recently the molecular mechanisms of exosome biogenesis. Our current ...