Identification of candidate therapeutic long non-coding RNA genes in the pathway TP53 Ghent University
Neuroblastoma is a pediatric extracranial tumor, derived from neural crest progenitor cells normally giving rise to the sympathetic nervous system. This enigmatic malignancy shows clinical outcomes ranging from spontaneous regression and long-term survival, to aggressive high-risk tumors resulting in death in a high percentage of cases. Although patients having the worst prognosis are subjected to multimodal therapy, the survival rate still ...