Projects
Self-criticism and affective spectrum symptoms during adolescence: The role of the parenting environment, genetic vulnerability, and their interaction KU Leuven
Studies have shown that depression and functional somatic disorders (e.g., chronic pain and fatigue conditions) are highly comorbid and tend to co-aggregate within families. Hence, researchers argue that depression and functional somatic disorders belong to an “affective spectrum” of disorders that possibly share etiological mechanisms. A growing body of research suggests that self-criticism (i.e., a personality dimension marked by high ...
Constructing Adolescent Minds in Experimental Fiction for Young Readers: A Genetic Approach to Aidan Chambers' Dance series. University of Antwerp
Determination of genetic and therapeutic dependencies of patient-derived models of brain cancer KU Leuven
Creating Suspense Across Versions: Genetic Narratology and Stephen King's IT. University of Antwerp
The human genetic and immunological determinants of the clinical manifestations of SARS-CoV-2 infection: Towards personalised medicine KU Leuven
The consequences of SARS-CoV-2 exposure range from a lack of infection to lethal COVID-19. This immense inter-individual clinical variability is the key scientific and medical enigma in the field. While age and certain co-morbidities are known to influence disease outcome, these parameters do not explain all variation. In addition, there are other SARS-CoV-2 phenotypes of clinical importance: multisystem inflammatory syndrome in children and ...
Transcriptome profile of the human placenta: in search of maternal and fetal genetic factors associated with preterm birth. Ghent University
Preterm birth is defined as childbirth before 37 completed weeks of pregnancy. It is the
leading cause of perinatal morbidity and mortality, leading to high costs in care and long-term disability. It accounts for 5-12 % of all live births worldwide. Multiple factors, both endogenous and exogenous to the mother seem to play a role. Genetic factors appear to be involved, as apparent from disparities between racial groups and on familial ...
Metafiction and the writing process. A genetic approach to 'autography' in Samuel Beckett's Molloy, Malone meurt, and L'Innommable. University of Antwerp
A genetic approach for the study of Notch signaling in normal and malignant hematopoiesis in human Ghent University
The immune system is our body’s major defense mechanism against invading pathogens,
as well as against tumor cells. One of the critical white blood cells that plays a central role in the immune system are T lymphocytes, cells that are generated from blood forming
stem cells through a process that is driven by the Notch signaling pathway. In a number of
clinical cases, for example after radio- and/or chemotherapy prior to stem ...