Projects
Iron deficiency anaemia in pregnancy: Evaluation of the effectiveness and safety of intravenous ferric carboxymaltose and oral ferrous sulphate in a low-middle income country Institute of Tropical Medicine
Strategies to Reduce the Iron Intake During the Brewing Process with respect to Flavour Stability KU Leuven
Flavour stability represents a key aspect of beer quality, but remains a major challenge for brewing science and the brewing industry. The gradual deterioration of the organoleptic qualities of beer during ageing significantly diminishes its value in several respects, including market appeal, palatability and overall drinkability. While beer is inherently unstable due to its complex composition, strategic measures can be implemented to ...
Is Contaminant Iron (Fe) Nutritionally Important? Tef and Wheat as Model Cereal Grains Ghent University
Iron is an important micronutrient to be in good health, and many people suffer from iron deficiencies, especially those that are mainly dependent on a plant (cereal)-based diet. Several strategies are done in the past to increase the iron content in the foods, although the efficiency of its absorption (determined as bioaccessibility) is still very limited. This is for sure the case for plant based products, and cereals, as they contain some ...
Effect of iron status and red cell indices on exercise capacity and response of exercise training University of Antwerp
New iron sources for organic piglets Research Institute for Agriculture, Fisheries and Food
How can piglets' iron requirements be met naturally and organically, without an iron injection? This research question arises from a potentially stricter approach to organic certification. If in the future the certification organizations consider the provision of an iron injection as a medical treatment, which is already the case in countries such as France, this will be problematic for ...
BEADS - Benthic fauna as drivers of ice-to-ocean iron transport in Arctic Fjords Ghent University
The ocean is the largest sink of CO2 and regulates the global climate. Marine primary production is a key process for CO2 removal and is limited by iron availability in large parts of the ocean. Marine iron concentrations are directly controlled by their sources to the ocean. Meltwaters from glaciers are considered as significant iron sources. To reach the ocean this glacial meltwater transits through fjords. When iron encounters oxygenated ...
Polyamine and iron interplay at the interface between mitochondria and lysosomes with its putative implications for Parkinson’s disease. KU Leuven
Parkinson's disease (PD) is a progressive neurodegenerative disease whose main symptoms are the consequence of the loss of dopaminergic neurons in the substantia nigra. Its pathological hallmarks include protein aggregation and lysosomal and mitochondrial dysfunction. In addition, excess iron accumulation in dopaminergic neurons and defects in the metabolism of polyamines have been implicated in the pathology of PD. Multiple studies suggest ...
THE ELUCIDATION OF SUBCELLULAR IRON HOMEOSTASIS IN CANDIDA ALBICANS IN THE PRESENCE AND ABSENCE OF THE ANTIFUNGAL DRUG FLUCONAZOLE KU Leuven
C. albicans forms a part of the natural human microbiome and is predominantly found in the gastrointestinal tract, on the skin and on mucosal surfaces. However, in some circumstances, C. albicans is able to switch to a pathogenic lifestyle resulting in candidiasis. Especially immunocompromised patients as well as patients undergoing transplant surgery are the main risk groups for a Candida infection. A problem currently observed in hospitals ...
On the limits of ab initio and DFT methods for bioinorganic iron models KU Leuven
Iron is one of the most common metal centers in bioinorganic chemistry. The many processes in which iron plays a part are governed by its electronic structure. Particularly, the different accessible oxidation and spin states can display distinct physical and chemical properties. In this regard, computational chemistry provides an invaluable tool for the study of the electronic structure of the different iron centers. However, not all the ...