Projects
The next generation of transmission electron microscopy: from biomedicine to nanomaterials. A state-of-the art electron microscopy system for cryo-EM and correlative light and electron microscopy. Hasselt University
Multidisciplinary installation of a polyvalent microscope for transmitted light, phase contrast and fluorescence microscopy KU Leuven
Novel microscope designs for fast and highly adaptable fluorescence microscopy. KU Leuven
3D super-resolution correlative light and electron microscopy on a dedicated CLEM microscope and development of an automated data acquisition KU Leuven
Fluorescence microscopy can provide information about location of specific protein molecules, by tagging them with fluorescent moieties, or by labeling them with fluorescent antibodies. However, this information is constraint by the limited resolution of the fluorescence microscope as well as by the absence of cellular context on the nano-scale. Therefore it is necessary to employ correlative light and electron microscopy (CLEM), which ...
Super-resolution optical microscopy and optical trapping of nanoparticles in the vacuum chamber of a scanning electron microscope KU Leuven
In 1986, Ashkin and coworkers proposed the use of tightly focused laser beams to manipulate individual micro-scale objects such as microparticles. Typically, micro- and nano-scale objects freely diffuse in the bulk solution. In the presence of an optical field, the particles can be trapped in the focal spot as a trapping potential is generated there. When several nanoparticles are trapped, they will generate an assembly inside the focus. ...
Disposable sample holder with integrated optics for enabling Light Sheet Microscopy on standard light microscopes Ghent University
The human body is a true wonder. It is composed by an average of A.G trillion cells, subdivided in more than MNN different cell types, each with its function and its own specialization. Yet, life is possible only if those cells manage to communicate and closely collaborate with each other, to reach their common goal. Clearly, collaboration is the key to evolution and progress. This is no different in science. The technological progresses of ...