Projects
Full field optical coherence microscopy (FF-OCM) with ultrahigh resolution for 3D microscopic monitoring of biological tissues. KU Leuven
Total internal reflection fluorescence microscope (TIRF microscope). KU Leuven
A correlative microscopy approach for intracellular structures under cryogenic conditions based on Single-Molecule Localization Microscopy and X-ray nanoscopic imaging. Ghent University
Super-resolution microscopy techniques allow the visualization of antibodies - markers for locating intracellular and extracellular proteins - with a resolution of <10 nm, allowing the visualization of the internal structure of cells. Stochastic recently developed, relatively inexpensive, but powerful super-resolution microscopy techniques. project, we want to build a cost-efficient dual wavelength STORM microscope (the setup can ...
New microscopy tools for catalysis. KU Leuven
Linking statistical crystal plasticity modelling of TRIP to the microstructural evolution probed by 3D X-ray microscopy KU Leuven
The hallmark of TRIP materials is their exceptional combination of toughness and formability rooted on the mechanically induced transformation of austenite to martensite. The gradual transformation to an intricate mixture of austenite and martensite bestows an exceptional balance of strength and ductility to these materials. However, the resulting complex interplay between the concomitant phase transformation, plastic slip and the local 3D ...
Implementation of ratiometric time-lapse fluorescence microscopy for studying metabolic changes in high hydrostatic pressure stressed cells of Escherichia coli O157:H7 KU Leuven
In contrast to (macroscopic) plate count methods, the increased intra- and intercellular resolution provided by current live (microscopic) cell biology approaches allows a much more detailed and online mechanistic dissection of individual cellular behavior in stressed populations of foodborne pathogens, which will become essential to better predict and improve the efficacy of current minimal (non-thermal) processing and preservation practices ...
Advanced illumination techniques for high-contrast highresolution fluorescence and scattering microscopy Ghent University
In light microscopy an object is illuminated with a lamp or a laser and the transmitted,
reflected or fluorescent light is detected to get information on the object. In the project two approaches will be developed to study small particles and their interaction with living cells: Light Sheet Fluorescence Microscopy and Complex Beam Scattering Microscopy.
In standard fluorescence microscopy the entire sample is illuminated and there ...
3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MIND KU Leuven
The VIB BioImaging Core is expanding its infrastructure to
create a workflow to zoom in on molecular processes that
underlie neurodegenerative diseases. The infrastructure
includes a new super-resolution microscope, which can
visualize processes inside the cell using light microscopy at
a much higher resolution than what is currently available.
The microscope also integrates a laser that can mark areas
in ...