Projects
Quantification and cross-validation of biomarkers for multi-parametric / multi-modal imaging in pre-clinical models of infectious diseases KU Leuven
The current available tests for diagnosing human brain disorders have different disadvantages and drawbacks, each single disease can be excluded by differential diagnosis, but no real certainty is achievable. Therefore, the medical community feels the urge to develop a strategy able to identify quantitative biomarkers for the etiological diagnosis of diseases, their staging and potential therapy monitoring. Preclinical models of the brain ...
Gnotobiotic Artemia brine shrimp as a model for studying the transcriptional, translational and epigenetic mechanisms responsible for immune 'imprinting' against infectious diseases in invertebrates Ghent University
Invertebrates, including shrimps, rely on their innate immunity to fight against pathogens. Innate immunity lacks the ability to show high degree of specificity and long-lasting memory. However, few reports claimed that invertebrates show some form of immunological specificity and memory similar to that of adaptive immunity in vertebrates. Using the gnotobiotic brine shrimp Artemia as model organism, this project aims to unambiguously prove ...
Developing and optimizing stochastic individual-based infectious disease simulation models by parallel multicore computing techniques. University of Antwerp
Infectious disease triggers in humanized models of synucleinopathy KU Leuven
Synucleinopathies such as Parkinson's disease and Multiple System Atrophy (MSA) are characterized by the accumulation of É‘-synuclein protein and the progressive loss of neurons and associated cognitive or motor functions. Neuroinflammation has been shown to play a crucial role in the development of these diseases. Additionally, infectious diseases have also been linked to the onset of neurodegeneration. The KU Leuven team of prof. Peelaerts ...