Projects
Characterizing genes and molecular mechanisms involved in frontotemporal lobar degeneration (FTLD) using an integrated approach of molecular genetics and functional genomics. University of Antwerp
A molecular epidemiological approach to senescence: influence of early life environmental exposure on (epi) genetics Hasselt University
Molecular genetics and biomarker research of frontotemporal lobar degeneration supported by robust biosampling and biobanking strategies. University of Antwerp
Molecular genetics of mantle cell lymphoma. KU Leuven
Molecular genetics of early-onset Alzheimer's disease. University of Antwerp
Next generation sequencing in molecular genetics for hereditary breast cancer, an emerging new strategy Ghent University
Germline BRCA1&2 mutations do not explain a large proportion of the families with hereditary breast cancer. This bilateral research project aims to gain insight in the role of ATM, BRIP1, CHEK2 and PALB2 mutations in Flemish and Québec breast cancer families using the next generation sequencing (NGS) technology. The expertise of both research groups in complementary: the Flemish group will be strongly involved in the development of an ...
Molecular genetics and functional study of HSPB8 mutations associated with hereditary motor neuropathy. University of Antwerp
Molecular Genetics and Biology of Intermediate Charcot-Marie-Tooth neuropathy. University of Antwerp
Molecular characterization of genetic events driving development of peripheral T cell lymphoma KU Leuven
Peripheral T cell lymphoma (PTCL) is a form of blood cancer that develops from mature T cells, a kind of white blood cells. These T cells are growing uncontrollably, thereby forming a tumor that is mostly located in the lymph nodes. PTCL patients are currently treated with chemotherapy, but the chances of survival are only 30%. Therefore, there is a high clinical need for new therapeutic options for these patients. With this research project, ...