Molecular genetic research into the complex genetics of frontotemporal lobar dementia. University of Antwerp
Frontotemporal lobar degeneration (FTLD) is a form of dementia characterized by progressive alternation of personality and/or language problems. In up to 50% of FTLD patients a family history of the disease is observed indicating an important role of genetic factors to the development of the disease. Causal mutations are found in the PGRN, MAPT, VCP and CHMP2B genes, which explain now 10 to 20% of FTLD patients. In this project I seek to ...