Lassa virus: unravelling the within-host evolutionary dynamics of acute and persistent infections and the virulence evolution among hosts KU Leuven
Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus (LASV) and one of the priority diseases listed by the World Health Organization. The high incidence in Nigeria with an annual rise of 200-300 cases since 2017 and a case fatality rate of 20% highlight the urgent need to intensify LASV research. To this end, two major longitudinal studies in acute and surviving Lassa fever individuals were initiated in Nigeria in 2018 ...