Projects
Genetic diversity and molecular epidemiology of hantaviruses KU Leuven
Hantaviruses are zoonotic pathogens responsible for hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) after human transmission. Pathogenic hantaviruses primarily have rodents as their reservoir, with humans acting as an accidental dead-end host. The actual hantavirus host range appears to be much broader with hantaviruses detected in shrews, moles, bats, reptiles, and fish. In Western, Northern, and Central ...
Molecular and genetic dissection of microbial inactivation by high pressure. KU Leuven
Molecular genetic analysis of genes responsible for inherited axonal peripheral neuropathies. University of Antwerp
Paget's disease of bone: molecular genetic investigation of the NFkB signaling regulating genes CBL, CBLB, and NR4A1 and functional validation in vitro and in Danio rerio. University of Antwerp
EPISTOP: Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic model of epilepsy – tuberous sclerosis complex Vrije Universiteit Brussel
...
Novel genetic tools to study the molecular basis of drug resistance in Trypanosoma congolense Institute of Tropical Medicine
Molecular genetic analysis of fever-related epileptic syndromes. University of Antwerp
COGEVAB: New COmputational tools at the molecular scale for studying effects of GEnetic VAriants on drug Binding Ghent University
Protein binding sites are functionally important regions on protein surfaces, through which proteins interact with other molecules, such as drugs Sequence variants are variations in a single nucleotide that occur at a specific position in the genome and can alter proteins, sometimes resulting in dysfunctional proteins causing various diseases and changing individual's response to drugs This proposal will focus on the development and use of ...