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Malaria control by antivectorial measures in a zone of chloroquine-resistant malaria: a successful programme in a rice growing area of the Rusizi valley Institute of Tropical Medicine

M. Coosemans, M Barutwanayo
Within a large project for the socio-economic development of the rice growing area of the Rusizi valley in Burundi, a malarial control programme has been set up. This programme has several components: improvement of curative services, promotion of use of impregnated mosquito nets, and use of environmental engineering and indoor spraying with residual insecticides to control infection

Respiratory virus-associated severe acute respiratory illness and viral clustering in Malawian children in a setting with a high prevalence of HIV infection, malaria, and malnutrition Institute of Tropical Medicine

Ingrid Peterson, Naor Bar-Zeev, Neil Kennedy, Antonia Ho, Laura Newberry, Miguel A SanJoaquin, Mavis Menyere, Maaike Alaerts, Gugulethu Mapurisa, Moses Chilombe, et al.

BACKGROUND:  We used data from 4 years of pediatric severe acute respiratory illness (SARI) sentinel surveillance in Blantyre, Malawi, to identify factors associated with clinical severity and coviral clustering.

METHODS:  From January 2011 to December 2014, 2363 children aged 3 months to 14 years presenting to the hospital with SARI were enrolled. Nasopharyngeal aspirates were tested for influenza virus and other respiratory viruses. ...

Mangrove horseshoe crab (Carcinoscorpius rotundicauda Latreille, 1802) populations reveal genetic break in Strait of Malacca, with connectivity along southern coasts of Peninsular Malaysia Vrije Universiteit Brussel

Nur Fairuz-Fozi, Ludwig Triest, Nurul Ashikin Mat Zauki, Anne Marie Kaben, Bryan Raveen Nelson, Anil Chatterji, Mohd Fadzil Akhir, Behara Satyanarayana, Farid DahdouhGuebas

The mangrove horseshoe crab, Carcinoscorpius rotundicauda, has divergent populations between the east and west coasts of Peninsular Malaysia, with the southern coast acting as a land barrier. The actual position of such a genetic break along Peninsular Malaysia as well as the connectivity status of the southernmost C. rotundicauda populations with east and west coast populations remain unexplored, however. The aim was to investigate the ...

Serological markers to measure recent changes in malaria transmission - a promising tool towards malaria elimination Institute of Tropical Medicine

Karen Kerkhof
Malaria, a vector-borne disease caused by a Plasmodium parasite, is one of the most deadly infectious diseases. Despite large progress in malaria control, malaria remains an important public health concern. For countries heading to elimination, evaluation and implementation of additional malaria control tools is crucial. However, follow-up of malaria prevalence and incidence using classical malariometric tools becomes challenging in low malaria ...

Reactive, self-administered malaria treatment against asymptomatic malaria infection: results of a cluster randomized controlled trial in The Gambia Institute of Tropical Medicine

Joseph Ugbu Okebe, Edgard D. Dabira, Fatou Jaiteh, Nuredin Ibrahim Mohammed, John Bradley, Ndey-Fatou Drammeh, Amadou Bah, Yoriko Masunaga, Jane Achan, Joan Muela Ribera, et al.

BACKGROUND: Selectively targeting and treating malaria-infected individuals may further decrease parasite carriage in low-burden settings. Using a trans-disciplinary approach, a reactive treatment strategy to reduce Plasmodium falciparum prevalence in participating communities was co-developed and tested.

METHODS: This is a 2-arm, open-label, cluster-randomized trial involving villages in Central Gambia during the 2017 and 2018 malaria ...

Accuracy of PfHRP2 versus Pf-pLDH antigen detection by malaria rapid diagnostic tests in hospitalized children in a seasonal hyperendemic malaria transmission area in Burkina Faso Institute of Tropical Medicine KU Leuven

Jessica Maltha, Issa Guiraud, Palpouguini Lompo, Bérenger Kaboré, Philippe Gillet, Chris Van Geet, Halidou Tinto, Jan Jacobs

BACKGROUND: In most sub-Saharan African countries malaria rapid diagnostic tests (RDTs) are now used for the diagnosis of malaria. Most RDTs used detect Plasmodium falciparum histidine-rich protein-2 (PfHRP2), though P. falciparum-specific parasite lactate dehydrogenase (Pf-pLDH)-detecting RDTs may have advantages over PfHRP2-detecting RDTs. Only few data are available on the use of RDTs in severe illness and the present study compared ...

Understanding malaria persistence: a mixed-methods study on the effectiveness of malaria elimination strategies in South-Central Vietnam Institute of Tropical Medicine

Thi Thuan Nguyen, Charlotte Gryseels, Thanh Duong Tran, Tom Smekens, Rene Gerrets, Xuan Xa Nguyen, Koen Peeters

Despite the scale-up of vector control, diagnosis and treatment, and health information campaigns, malaria persists in the forested areas of South-Central Vietnam, home to ethnic minority populations. A mixed-methods study using an exploratory sequential design was conducted in 10 Ra-glai villages in Bac Ai district of Ninh Thuan province to examine which social factors limited the effectiveness of the national malaria elimination strategy in ...