Zebrafish embryos as a unique model host organism to study in vivo Candida albicans biofilm development. KU Leuven
Candida albicans is a commensal organism in most humans. The possible beneficial function for the host is unknown. Under some conditions, such as a weakened immune system, this organism can become a deadly pathogen. For this it has a large array of virulence factors, such as morphogenesis and the production of different types of hydrolyses. Another important virulence factor is biofilm formation. Biofilms are three-dimentional structures ...