Projects
Belgian Medical Genomics Initiative (BeMGI) Ghent University
The aim of the BeMGI project is to:
(i) understand the biology of disease by exploiting the most advanced genomic tools.
(ii) predict clinical outcome from genomic information and fulfil a pilot role towards concerted integration of genomic information in clinical care in Belgium.
(iii) prepare the next generation of genomics researchers, informing medical practitioners, and conducting public outreach. ...
MOLECULAR DIAGNOSTICS IN AUTISM SPECTRUM DISORDER: NEXT GENERATION SEQUENCING AND FACIAL PHENOTYPING IN MEDICAL GENETICS KU Leuven
Despite considerable progress in the genetics of autism spectrum disorder (ASD) in the past decade, molecular diagnostics for patients with ASD remains a great challenge due to the complex genetic architecture of ASD. In clinical genetics, an etiological distinction is usually made between ASD patients with Mendelian causes (i.e. driven by a highly penetrant rare variant) and patients with multifactorial causes (i.e. driven by many genetic ...
Subsidy for Center Medical Genetics. University of Antwerp
Subsidiation centers for medical genetics 2010 Ghent University
Represents a yearly financial incentive from the government to the genetic centres for support and promotion of genetic counselling activities on a multidisciplinary basis, including focus on psychological support
GENOmics in MEDicine: From whole genome sequencing towards personalized medicine (GENOMED). University of Antwerp
Personalized functional genomics in Mendelian diseases: from DNA variants to clinical and bioethical implications Ghent University
This proposal deals with personalized functional genomics in Mendelian disorders. We will tackle non-‐coding variation by NGS approaches. We will use state-‐of-‐the-‐art knockdown, knockout and
rescue experiments in model organisms. Furthermore, functional assays in patient-‐derived cellular models such as hiPSCs will lead to understanding of mutations and mechanisms.
In addition, we will optimize PGD-‐NGS. ...
ZAP post in functional genomics and genomic bio-computing Ghent University
ZAP post in functional genomics and genomic bio-computing (Jo Vandesompele)
Genomic Medicine: Translation of Whole Genome Analyses to Health Genomics KU Leuven
The translational Genomic Medicine IOF program is situated at the interface between clinical practice and strategic fundamental research and in a tight junction with the CME. The program was partitioned in three discrete lines of research and valorisation: A first line of research is focusing on novel approaches for postnatal diagnosis using massive parallel sequencing and whole genome sequencing. Both Prof. Vermeesch and Prof. Matthijs have ...